explain how viral genome composition affects its replication cycle? for example dsDNA replicated differently than ss + sense RNA
Answer=
The viral genome composition affects its replication cycle in following ways:
Viruses are biological entities incapable of existing ina a cell-independent manner.viruses infecting eukaryotic cells offer all possibilities of genome composition,being either DNA or RNA,single stranded or double stranded ,circular or linear ,segmented or nonsegmented .
therefore viruses have evolved a variety of replication strategies to convert viarl genome information into infectious viral particles.
Viral genomes are replicated,expressed & assembled in association with intracellular structures that are formed or recoganized by viral & cellular macromolecules.these complex molecular assemblies occupy either cytoplasmic or nuclear sites,where the viral genome & viral & cellular proteins accumulate.
The molecules & activities that are associated with these compartments are diverse but ,invariably ,include components that direct viral genome replication & expression.
Formation of compartments where viral genomes are replicated & assembled has been described for negative -sense RNA (-),Double stranded RNA (dsRNA) & positive -sense RNA (+) viruses.
In the case of positive strand RNA genomes of variety of virus families ,RNA replication is associated with extensive reorganization & generation of single or double membranous structures coopted by membrane associated viral replicase complexes (RCs).
RCs formed by RNA (+) viruses
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