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12. (2 pts) Which one of the following statements is FALSE? A. In feedback inhibition, the product of a pathway inhibits an early enzymatic step. B. Protein kinases add inorganic phosphate (P) to a Ser, Thr, or Tyr C. An enzyme could be activated or inactivated by a protein phosphatase. D. AMP stimulates glycolysis and inhibits gluconeogenesis. E. Insulin stimulates activation of glycogen synthase and represses its inactivation. (4 pts) Complete the following sentences by circling the appropriate term from the three choices provided. 13. A. Prior to entering the citric acid cycle, pyruvate must be oxidatively decarboxylated to B. In the first reaction of the citric acid cycle, a two-carbon acetyl group is covalently C. In addition to three molecules of NADH, each turn of the citric acid cycle produces D. All citric acid cycle enzymes are water soluble except for membrane-associated: form: coenzyme A acetyl-CoA acetate linked to four-carbon: oxaloacetate malate isocitrate one molecule of: FADH FADH2 FMN citrate synthase fumarase succinate dehydrogenase
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12. The answer for this question is E. Because the insulin could promote only the activation of glycogen synthase and could not represses its inactivation.

13A. Prior to entering the citric acid cycle, pyruvate must be oxidatively decarboxylated to form acetyl CoA

13B. In the first reaction of citric acid cycle, a two carbon acetyl group is covalently linked to four carbon oxaloacetate.

13C. In addition to three molecules of NADH, each turn off the citric acid cycle produces one of FADH2

13D. All citric acid cycle enzymes are water soluble except for membrane associated succinate dehydrogenase

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