Can someone quick answer/check these questions? Thank you, will rate! (the answers that I have came up with are in bold) Please help
51- Glycogenesis involves the following steps
a) isomerisation
b) activation
c) elongation or coupling
d) branching
e) all of the above
52 During the breakdown of glycogen, free glucose is formed from
A. the reducing end.
B. the non-reducing end.
C. glucose residues in an a 1-->4 linkage to the chain.
D. glucose residues in an a 1-->6 linkage to the chain.
E. hydrolysis of glucose 1-phosphate.
57-In the following pathway for conversion of glucose to glycogen, what is compound X?
glucose --> glucose 6-P --> X --> UDP-glucose ---> glycogen
A. glucose 6-pyrophosphate
B. glucose 1-phosphate
C. glucose 1,2-bisphosphate
D. fructose 6-phosphate
E. no intermediate is missing.
58. Theoretically, the maximum number of moles of ADP (or equivalent) phosphorylated to ATP (or equivalent) as one mole of glucose is completely oxidized to carbon dioxide and water in a liver cell is
A. 0
B. 2
C. 12
D. 24
E. 38
59. The enzyme that catalyzes the substrate-level phosphorylation of GDP to GTP in the TCA cycle is
A. 3-phosphoglycerate kinase.
B. succinyl-CoA synthase.
C. pyruvate kinase.
D. alpha ketoglutarate dehydrogenase.
E. succinate thiokinase
60. The tricarboxylic acid cycle is initiated by the condensation of
A. NAD and malate.
B. pyruvate and oxaloacetate
C. NAD and citrate.
D. acetyl-CoA and oxaloacetate.
E. acetyl-CoA and pyruvate.
64 Which enzyme complex in the TCA cycle requires the cofactors thiamine pyrophosphate, lipoic acid, CoA, FAD and NAD+?
A Citrate synthase
B a-ketoglutarate dehydrogenase
C Succiny-CoA synthetase (succinate thiokinase)
D Malate dehydrogenase
E Fumarase
65. You are the team physician for your local women's
soccer team. Some of your new recruits have been disabled due to
injury for the past four months and are about to start a
conditioning program. Since their aerobic fitness is crucial to the
stamina needed for the game of soccer, you put them on a
progressive interval running program. As their aerobic fitness
increases, which of the following enzymes in their skeletal muscle
do you expect to mirror that increase?
A. Lactate dehydrogenase.
B. PEP carboxykinase.
C. Transaminase.
D. Hexokinase.
E. Succinate dehydrogenase.
66. Which of the following enzyme systems is most
analogous to the pyruvate dehydrogenase complex?
A. malate dehydrogenase
B. succinate dehydrogenase
C. fumarase
D. isocitrate dehydrogenase
E. alpha-ketoglutarate dehydrogenase
67. Which enzyme would be impaired in a biotin
deficiency?
A. fructose 1,6-bisphosphatase.
B. pyruvate kinase.
C. PEP carboxykinase.
D. pyruvate carboxylase.
E. malate dehydrogenase
68- Which of these statements is FALSE?
a) H type LDH subunits predominates in aerobic tissues such as heart muscle
b) M type LDH subunits predominates in anaerobic tissues such as skeletal muscle
c) H4 LDH has a low Km for pyruvate and is inhibited by high levels of pyruvate.
d) The M4 LDH enzyme has a high Km for pyruvate and is not inhibited by pyruvate.
e) The M type LDH is utilized for oxidizing lactate to pyruvate
Ans 51 e) All of the above
Gkycogenesis is the process in which glucose is formed out of glycogen .
The process involves activation of insulin followed by isomerization. Then UTP is converted into UMP to couple with glucose-1-phosphate . The branching occurs by the frmation of alpha 1-6 bonds.
Can someone quick answer/check these questions? Thank you, will rate! (the answers that I have came...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? :a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. α-ketoglutarate dehydrogenase complex\}c. citrate synthase10. Name the enzyme catalyzing the following reaction:a. PEP carboxykinaseb. pyruvate kinasec. malic enzymed. pyruvate carboxylase11. Name the enzyme that catalyzes the reaction:glyoxylate +CH3CO-SCoA → malate + HSCoAa. malate synthaseb. succinate thiokinasec. aconitased. isocitrate
What type of gradient is critical to ATP formation by oxidative phosphorylation?A.sodium ionB.chloride ionC.protonD.potassium ionE.None of the answers is correct.Which of the following citric acid cycle intermediates would become depleted if malonate, a competitive inhibitor of succinate dehydrogenase, were present?A.citrateB.α-ketoglutarateC.succinateD.malateE.None of the answers is correct.Which of the following correctly pairs a coenzyme with the enzyme of the pyruvate dehydrogenase complex with which it is associated?A.coenzyme A: pyruvate dehydrogenaseB.NAD+: dihydrolipoyl dehydrogenaseC.lipoic acid: pyruvate dehydrogenase kinaseD.thiamine pyrophosphate: dihydrolipoyl dehydrogenaseE.FAD: dihydrolipoyl transacetylaseWhich of...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? : a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 10. Name the enzyme catalyzing the following reaction: COOH + GTP - PEP + CO2 + GDP C=0 CH2 COOH a. PEP carboxykinase b. pyruvate kinase d. pyruvate carboxylase c. malic enzyme 11. Name the enzyme that catalyzes the reaction: glyoxylate + CH3CO-SCOA -- → malate +...
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
32. The gluconeogenic precursor thereby generated is alpha-ketoglutarate. The pathway e pathway by which it can be converted to glucose is: Enzyme alpha-ketoglutarate dehydrogenase succinyl-CoA synthetase succinate dehydrogenase Product succinate L-malate malate dehydrogenase phosphoenolpyruvate 3-phosphoglycerate glyceraldehyde-3-phosphate 0 enolase phosphoglycerate mutase phosphoglycerate kinase triose phosphate isomerase fructose-1,6-bisphosphate ctose bisphosphatase glucose-6-phosphate glucose-6-phosphatase
The number of electrons produced by one cycle of Krebs is 6 b. 8 c. 4 d. 2 The Ala that comes from the muscle is returned to the muscle as pyruvate c. glucose glutamate d. a-ketoglutarate Oxaloacetate enters the urea cycle as citrulline c. glutamate aspartate d. fumarate The oxidation of pyruvate to AcCoA uses similar cofactors as the oxidation of malate succinate a-ketoglutarate isocitrate The enzyme that requires FAD as cofactor is...
1. The enzyme responsible for the substrate level phosphorylation in the citric acid cycle is: a succinate dehydrogenase b. a-ketoglutarate dehydrogenase c. succinyl thiokinase d. isocitrate dehydrogenase e. aconitase 2. Which of the listed enzymes of the TCA cycle does not represent a regulatory enzyme?: a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 3. Oxidative decarboxylation of pyruvic acid is regulated by: a. cyclic AMP-dependent mechanism b. cyclic AMP-independent mechanism 4. The...
Please choose the BEST ANSWER. No cell phones, web or cameras, please. 1. Each of the following enzymes functions in both glycolysis and gluconeogenesis except: A) 3-phosphoglycerate kinase B) aldolase C) enolase D) phosphofructokinase-1 E) phosphohexose isomerase During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD if glycolysis is to continue. The most important reaction involved in this reoxidation of NADH is: 2. A) dihydroxyacetone phosphate> glycerol 3-phosphate B)...
10.Which statement regarding the transcriptional regulation of PEP carboxykinase is false A. The promoter region of the PEP carboxykinase gene has binding sites for more than a dozen transcription factors B. Transcription and degradation are the primary means of regulating PEP carboxykinase gene C . A sterol regulatory binding element protein decrease expression of the PEP carboxykinase gene D. Insulin increase expression of the PEP carboxykinase gene 11. Glycogenesis - A. Occurs only in the liver and muscle B. Begins...
6. In question 5, what is the most important reaction involved in formation of lactate? A) dihydroxyacetone phosphate glycerol 3-phosphate D) pyruvate → lactate B) oxaloacetate → malate E) isocitrate → a-ketoglutarate C) glucose 6-phosphate → fructose 6-phosphate 7. During the process in question 5 (the rapid rise in lactate concentration), the NADH must be reoxidized to NAD+. Which of the following enzymes will be most affected if NADH is not reoxidized? A) Pyruvate kinase. C) Phosphofructokinase-1. E) aldolase. B)...