Question

4. Hair grows at a rate of 20 cm/year. All this growth is concentrated at the base of the hair fiber, where a-keratin filaments are synthesized inside living epidermal cells and assembled into ropelike structures. The fundamental structure element of a-keratin is the a-helix, which has 3.6 amino acid residues per turn and a rise of 5.4 angstroms per turn. Assuming that the biosynthesis of the a-helix of keratin is the rate-limiting factor in the growth of hair, calculate the rate at which peptide bonds of a keratin chains must be synthesized (in peptide bonds per second) to account of the observed yearly growth of hair.

Answer 1

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Ansores! There are 3.6 amino acids (AAS) pes turn and the rise is s.y&lturn, the length per AA of the & helix is , = 1.5A/AA 5.4 A / tuon 3-6 AA / tuon = 115 X10M/AA A growth rate of 20cm / year is equivalent to, 20cm 1 year (365 days (gr) (24h/day) (Comin/h) (Gos/min) 6.310*cmis-63X10-9 m/s (: converted the 365 dass into seconds). - 1 rate at which amino acids are Thus, the added is 6. 3x10 ml 1.58 10 AA = 42 AALS. 42 peptide bonds per second.