How does HIV coordinate gene expression for synthesis of viral proteins and structure?
HIV virus infects the cell containing the CD4 antigen.There is an interaction between gp120 and CD4 molecule on the host cell. There is also the interaction between CCR5 and CXCR4 receptors which helps the virus to enter the cell. The virus enters the macrophage and the monocytes.The RNA of the virus is trancribed into cDNA molecule and then integrated into the genome of the host cell. After the fusion of the virus into the host cell membrane the HIV genome is uncoated and the virus RNA is reverse trancribed using viral reverse transcriptase which is integrated into genome of the host cell. The dsDNA is then transcribed into RNA which is then translated into viral protein and is released with the lysis of the host cell.
How does HIV coordinate gene expression for synthesis of viral proteins and structure?
(Begins with viral genome and ends with proteins) Hint: Remember that retroviruses synthesize genetic information in the reverse direction. Order the terms to list the steps from HIV retroviral genome replication to protein synthesis. Select the correct steps (6 items) Drag and drop into the appropriate area) Central Dogma of a Retrovirus Begin with viral genome Translation of viral proteins by host ribosomes 1 (+) ssRNA genome dsDNA genome egration into host genome 2 RNA polymerase II transcription Reverse transcriptase...
What are SOS gene products? How are they induced? A. SOS proteins (RecA, SSB, uvrABC, etc); nicked DNA binds to the Lac repressor, causing its release and degradation, thereby triggering expression of the SOS genes B. SOS proteins are the heat-shock proteins; the “chi” sequence binds to some transcription factors inducing expression of these genes C. SOS proteins are only transcription factors that activate other genes; DNA damage causes induction of these transcription factors through single-stranded DNA binding proteins D....
Coordinate regulation of gene expression is important both in bacteria and eukaryotes. Operons are used to co-ordinate gene expression in bacteria but NOT eukaryotes. Explain why operons strategy does not work in eukaryotes.
The following sentences describe chromatin structure and how altering chromatin structure can affect gene expression. Complete each sentence using the words provided.In some cells, DNA combines with proteins to form a substance calledThe lowest level of chromatin structure consists of DNA wrapped twice around a group of histones to form a(n)The formation of nucleosomes may block the binding of transcription factors and RNA polymerase II to theThe structure of chromatin can be modified by altering either the DNA or the...
1. In retroviral replication (such as HIV) reverse transcriptase is used to convert viral ds RNA into viral ds DNA viral ss RNA viral mRNA viral ss DNA 2. Many viruses undergo an uncoating process prior to replication. Which statement depicts the uncoating process? the virus destroys the host nuclear membrane allowing it access to DNA the virus sheds its protein coat the virus shed its envelope when entering the cell via the cell membrane the virus sheds its...
What would be the immunodominant antigens in the structure of HIV? How does the new strain of HIV from gorillas (“P” variant) replicate compared to other strains? What would this mean for how the virus acts within the host?
Proteins vary dramatically in structure; DNA strands are very similar in structure. How does this observation about differences in structure relate to differences in function between the two classes of biological molecules? How does the rather simple structure of DNA contain the information for such a complex and varied collection of proteins?
What is transcript factor? How does transcript factor regulate gene expression?
What is transcript factor. How does transcript factor regulate gene expression
Where are the various locations that viral assembly can occur within the cell and how does the location of assembly relate to the location of the production/synthesis of the viral factors?