1. Which of the following statements is INCORRECT? a.PKA phosphorylates a protein to begin a cell...
1. Which of the following statements is INCORRECT?
a.PKA phosphorylates a protein to begin a cell response.
b. IP3 stays within the membrane and activates protein kinase C. Then protein kinase C phosphorylates a protein to initiate a cell response.
c.After GTP is added, the alpha sub-unit of the G-protein slides over to activate phospholipase C.
d.Calcium ions can directly initiate a cell response.
e.Lipophilic ligands bind to receptors in the nucleus which then attach to DNA.
Homework Answers
Option C is incorrect. Because in G protein coupled receptors pathway , after the GTP is added to the alpha subunit of the G protein it binds to the active adenylate cyclase enzyme. This enzyme is the key regulatory enzyme, which catalyzes the conversion of ATP into cAMP (cyclic adenosine monophosphate) which leads to increase in intracellular cAMP.
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1. Which of the following statements is INCORRECT?
a.PKA phosphorylates a protein to begin a cell...
open to look at all pictures Multiple Choice Which of the following are true of G...
open to look at all pictures
Multiple Choice Which of the following are true of G protein coupled receptors (GPCRs) A) peripheral membrane protein B) Activates G proteins on cytoplasmic side C) Receptors to lipid soluble hormones D) Binds ligands on cytoplasmic side Submit CASTILLO NAVA Invoice Soon Multiple Choice Which of the following are true of G proteins A) Are integral membrane proteins B) Works with G protein coupled receptors C) dimer D) On the exoplasmic side of membrane...
Match the following: 1. G-protein 2. Phospholipase kinase (PLC) 3. Diacylgylceral (DAG) 4. Calmodulin 5. Calcium...
Match the following: 1. G-protein 2. Phospholipase kinase (PLC) 3. Diacylgylceral (DAG) 4. Calmodulin 5. Calcium a. Binds to calcium and activates other proteins b. Stored in the smooth ER and binds to proteins to change their conformation c. Splits PIP2 into IP3 and DAG d. Activity is regulated by GTP and GDP e. Activates protein kinase C and is a part of PIP2
Indicate which of the events listed below belong to which part of the signal transduction pathway.*...
Indicate which of the events listed below belong to which part of the signal transduction pathway.* (6 Points) Signal Reception Signal Transduction Cellular Response Signal Termination receptor activation causes Ga to release GDP and bind GTP 0 a bind GTP TE STEEL 0 activated protein kinase enters nucleus to promote transcription. of a specific gene 0 0 adenylyl cyclase produces CAMP from ATP 0 0 0 ooo 0 0 0 adrenaline binds adrenergic receptor 0 - 0 CAMP activates protein...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
Last guy got it wrong - Thank you. 2. You discover a signal transduction pathway that...
Last guy got it wrong - Thank you.
2. You discover a signal transduction pathway that regulates actin polymerization. SigC is the ligand, which binds to and activates a receptor tyrosine kinase (RTK). Activation of the RTK leads to the activation of the Ras protein, which then activates the protein kinase PK1 that phosphorylates the RingA protein on S34. When SigC plasma membrane phosphorylated, RingA binds EXTRACELLULAR to the gene regulatory SPACE inactive Ras protein activated Ras protein protein, AP1....
Need help on these questions ? 1.) Steroid hormones trigger transcription of target genes by... ...
Need help on these questions ? 1.) Steroid hormones trigger transcription of target genes by... a. activating the release of Ca+2 ions that bind to and activate transcription factors. b. activating a kinase cascade that results in the activation of a transcription factor for a set of genes. c. binding directly to DNA and stimulating transcription. d. binding to nuclear receptors that act as transcription factors for specific genes. 2.) Which type of cell-surface receptor(s), when...
9. What happens when a trimeric G a. Ga separates from b. GB separates from the...
9. What happens when a trimeric G a. Ga separates from b. GB separates from the GaG protein is activated by the GpGy dimer dimer d. Ga, Gp, and Gy separate from each other e. The trimeric G protein localizes to the c. Gy separates from the GaGß dimer t nuceus se the folowing list to answer questions 10-13.Answers can be used more than once a. Endocytosis followed by degradation in lysosomes tqitination mediated by SOCS followed by degradation by...
Name 2ors L! You are inte finding protein are interested in understanding how Top5 expression is...
Name 2ors L! You are inte finding protein are interested in understanding how Top5 expression is regulated. Top5 is a microtubule protein. You study a cell line where Top5 expression is controlled by a signal, Ligl. When hinds to and activates the membrane bound recentor it activates the Ras protein, which activates atein kinase called PKF, which then phosphorylates Grp4 on T224. Grp4 is a gene regulatory Wotein that can only enter the nucleus when phosphorylated: Thos is not expressed...
9. Analyze the diagram below of a nuclear response for gene expression: Which of the following...
9. Analyze the diagram below of a nuclear response for gene
expression:
Which of the following is this cell using to control all of the
other events to regulate gene expression?
a. phosphate bonded to a transcription factor
b. phosphorylation cascade with multiple steps
c. specific hormone that initiates a response
d. transcription housed outside of the nucleus
10. Below is a model of a signal transduction pathway that results
in the transcribing of mRNA:
Referencing the model, what...
QUESTION 1 When cells stimulate other cells at long distances, it is referred to as: paracrine...
QUESTION 1 When cells stimulate other cells at long distances, it is referred to as: paracrine loops autocrine loops synaptic signaling endocrine signaling 1 points QUESTION 2 What region of a protein binds phosphorylated serines & tyrosines on another protein? SH2 domain ligand cAMP receptor monomers 1 points QUESTION 3 Activation of a serpentine receptor can lead to: cAMP generation GTP-binding of G proteins activation of Protein Kinase A all of the above 1 points QUESTION 4...
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Multiple Choice Which of the following are true of G protein coupled receptors (GPCRs) A) peripheral membrane protein B) Activates G proteins on cytoplasmic side C) Receptors to lipid soluble hormones D) Binds ligands on cytoplasmic side Submit CASTILLO NAVA Invoice Soon Multiple Choice Which of the following are true of G proteins A) Are integral membrane proteins B) Works with G protein coupled receptors C) dimer D) On the exoplasmic side of membrane...
Match the following: 1. G-protein 2. Phospholipase kinase (PLC) 3. Diacylgylceral (DAG) 4. Calmodulin 5. Calcium a. Binds to calcium and activates other proteins b. Stored in the smooth ER and binds to proteins to change their conformation c. Splits PIP2 into IP3 and DAG d. Activity is regulated by GTP and GDP e. Activates protein kinase C and is a part of PIP2
Indicate which of the events listed below belong to which part of the signal transduction pathway.* (6 Points) Signal Reception Signal Transduction Cellular Response Signal Termination receptor activation causes Ga to release GDP and bind GTP 0 a bind GTP TE STEEL 0 activated protein kinase enters nucleus to promote transcription. of a specific gene 0 0 adenylyl cyclase produces CAMP from ATP 0 0 0 ooo 0 0 0 adrenaline binds adrenergic receptor 0 - 0 CAMP activates protein...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
Last guy got it wrong - Thank you.
2. You discover a signal transduction pathway that regulates actin polymerization. SigC is the ligand, which binds to and activates a receptor tyrosine kinase (RTK). Activation of the RTK leads to the activation of the Ras protein, which then activates the protein kinase PK1 that phosphorylates the RingA protein on S34. When SigC plasma membrane phosphorylated, RingA binds EXTRACELLULAR to the gene regulatory SPACE inactive Ras protein activated Ras protein protein, AP1....
9. What happens when a trimeric G a. Ga separates from b. GB separates from the GaG protein is activated by the GpGy dimer dimer d. Ga, Gp, and Gy separate from each other e. The trimeric G protein localizes to the c. Gy separates from the GaGß dimer t nuceus se the folowing list to answer questions 10-13.Answers can be used more than once a. Endocytosis followed by degradation in lysosomes tqitination mediated by SOCS followed by degradation by...
Name 2ors L! You are inte finding protein are interested in understanding how Top5 expression is regulated. Top5 is a microtubule protein. You study a cell line where Top5 expression is controlled by a signal, Ligl. When hinds to and activates the membrane bound recentor it activates the Ras protein, which activates atein kinase called PKF, which then phosphorylates Grp4 on T224. Grp4 is a gene regulatory Wotein that can only enter the nucleus when phosphorylated: Thos is not expressed...
9. Analyze the diagram below of a nuclear response for gene
expression:
Which of the following is this cell using to control all of the
other events to regulate gene expression?
a. phosphate bonded to a transcription factor
b. phosphorylation cascade with multiple steps
c. specific hormone that initiates a response
d. transcription housed outside of the nucleus
10. Below is a model of a signal transduction pathway that results
in the transcribing of mRNA:
Referencing the model, what...
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