68-year-old man who collapsed while mowing lawn History: Roger Crocket, a 68-year-old man with a 40-pack-year smoking history and recent complaints of angina upon exercising, collapsed while mowing his lawn. Paramedics arriving at the scene found him unconscious, not breathing, and without a pulse. CPR was successfully performed and Roger was transported to the hospital. An ECG was suggestive of an anterior wall myocardial infarction, and he was given an intravenous solution of tissue plasminogen activator (TPA). Elevated blood creatine phosphokinase (CPK) levels measured over the next 2 days confirmed the diagnosis. Coronary angiography was performed a week later, revealing the following results:
Circumflex artery: 20% blocked
Right coronary artery 15% blocked
Left anterior descending artery (LAD): 95% blocked 6.
6.What is creatine phosphokinase (CPK) and why are elevated CPK levels in the blood suggestive of a myocardial infarction (heart attack)? What is tissue plasminogen activator (TPA), what is it used for, and how does it work?
Creatine kinase or creatine phosphokinase is an enzyme found in heart ,brain, skeletal muscle. Increased level of this enzyme is indicative of heart problem, as it is increased when heart muscle get damaged.
TPA is kind of protein found on endothelial cell of blood vessels it is used to dissolve blood clot and in improving blood flow
68-year-old man who collapsed while mowing lawn History: Roger Crocket, a 68-year-old man with a 40-pack-year...
Myocardial Infarction Patient Profile F.M. is a 68-year-old white man who comes to the emergency department (ED) in the early afternoon with a 2-day history of severe chest pain. The pain started on wakening the previous day. The pain increased during the night, but his wife could not convince him to go to the hospital. He comes to the ED today because the pain is severe and no longer relieved by rest. Subjective Data Describes recurring chest pain for the past 6 months that...
Mr. K. is a 57-year-old man who consulted his physician after noticing marked leg pains while playing golf. He had previously noticed increasing fatigue and discomfort in his legs associated with moderate exercise. When sitting for extended periods with legs dangling, his legs became red, and sometimes his feet felt numb. His history indicates he smokes cigarettes and is chronically overweight. His blood cholesterol and other lipid levels are abnormal, and his physician suspects peripheral atherosclerosis as the cause of...
Mr. K. is a 57-year-old man who consulted his physician after noticing marked leg pains while playing golf. He had previously noticed increasing fatigue and discomfort in his legs associated with moderate exercise. When sitting for extended periods with legs dangling, his legs became red, and sometimes his feet felt numb. His history indicates he smokes cigarettes and is chronically overweight. His blood cholesterol and other lipid levels are abnormal, and his physician suspects peripheral atherosclerosis as the cause of...
Mr. K. is a 57-year-old man who consulted his physician after noticing marked leg pains while playing golf. He had previously noticed increasing fatigue and discomfort in his legs associated with moderate exercise. When sitting for extended periods with legs dangling, his legs became red, and sometimes his feet felt numb. His history indicates he smokes cigarettes and is chronically overweight. His blood cholesterol and other lipid levels are abnormal, and his physician suspects peripheral atherosclerosis as the cause of...