Homework Answers
Cdks are Kinases whose activity is regulated throughout the cell cycle such that .it is high as the cell enters S and M phase but decreases at the end of mitosis.One method of inhibition is accomplished by restricted transcription of cyclins
Cdks are cyclin dpendent kinases that regulate the cell cycle at different checkpoints.CDK activity increases during S and M phase and is low in G1-G0 phase.Cyclins are needed for activation of CDKS.Cycins are controlled by transcription that help control CDKs
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Question 1 3 pts One Cdks are _whose activity is regulated throughout the cell cycle, such...
Dynamic phosphorylation/dephosphorylation is key to proper cell cycle control in that: (select all answers that apply)...
Dynamic phosphorylation/dephosphorylation is key to proper cell cycle control in that: (select all answers that apply) A. CAKs phosphorylate (and activate) CDK subunits. B. Wee1 kinase phosphorylates (and activates) CDK subunits. C. Cdc25 kinase phosphorylates (and activates) CDK subunits. D. Phosphorylation of the CKI Sic1 directs its subsequent ubiquitination and proteasomal degradation. E. Kinases phosphorylate (and activate) SCF, the ubiquitin ligase responsible for degradation of G1/S phase cyclins.
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is...
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is known as a proto-oncogene. True False QUESTION 2 Cytokinesis occurs after which stage or phase of the cell cycle? a. G2 b. S c. G0 d. G1 e. M phase QUESTION 3 During cell-cycle checkpoints, protein kinases known as CDKs phosphorylate target proteins only when they associate with a cyclin. True False QUESTION 4 During mitosis, many of the spindle fibers attach to chromosomes...
Cell cycle progression is controlled by the rhythmic accumulation and degradation of:
Question 3 Cell cycle progression is controlled by the rhythmic accumulation and degradation of:Question 3 options:CyclinsCyclin-dependent kinases (Cdks)BothQuestion 4 During metaphase of mitosis:Question 4 options:DNA is replicatedSister chromatids line up together on the equatorDNA is uncoiled and in useSpindle fibers are absentPreparation for cell division beginsQuestion 5 During cell division, cytokinesis is completed by the end of:Question 5 options:prophaseanaphasemetaphasetelophaseinterphaseQuestion 6 Crossing over or recombination most frequently occurs during:Question 6 options:prophase I of meiosismetaphase II of meiosisprophase of mitosistelophase of mitosisprophase II of meiosisQuestion 7 In...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to grow in size (a) extracellular signals that stimulate cell division. d) produced by mitotic cells to keep nearby neighboring cells from dividing 7.) Which of the following cyclins is most active during mitosis? (a) cyclin A (b) cyclin B (c) cyclin C (d) cyclin D 8) Which molecule inactivate itotic cyclin-CDK complexes using phosphorylation? (a) Cdc25 (b) Cdc6 (c) Weel (d) Helicase 9.) What...
Question 31 2.3 pts What feature characterizes cancer cells? carefully regulated cell cycle uncontrollable cell division...
Question 31 2.3 pts What feature characterizes cancer cells? carefully regulated cell cycle uncontrollable cell division respond to density-dependent and anchorage dependent inhibition o divide by meiosis produce cells which are different from themselves
Question 26 (1 point) How is cytokinesis in plant cells different from cytokinesis in animal cells?...
Question 26 (1 point) How is cytokinesis in plant cells different from cytokinesis in animal cells? Cytokinesis in plant cells requires formation of a cell plate; cytokinesis in animal cells requires formation of a ring of actin. Cytokinesis in plant cells occurs during G2; cytokinesis in animal cells occurs in the M phase of the cell cycle. Cytokinesis in plant cell results in one large cell with two nuclei; cytokinesis in animal cells results in two cells, each with one...
Inspired by Lee Hartwell's Nobel Prize (2001), you decide to study cell cycle regulation in yeast....
Inspired by Lee Hartwell's Nobel Prize (2001), you decide to study cell cycle regulation in yeast. You know that the expression of a cell cycle-associated kinase, Cdk24p, changes throughout the cell cycle, being very high in G 1/S and low in G2/M. Nevertheless, mRNA levels for CDK24 are constant throughout the cell cycle. You decide to study how this regulation occurs. You isolate a temperature sensitive mutant cell linethat fails to divide at the non-permissive temperature and notice that Cdk24p...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
Question 36 1 pts 36. You have a population of mammalian cells growing in media containing...
Question 36 1 pts 36. You have a population of mammalian cells growing in media containing enough growth factors. Which of the following graphs corresponds to these cells when their DNA content is analyzed 24 hours after they are induced to express high levels of a mutant form of Rb protein that cannot be phosphorylated? (Note: this cell line has its cell cycle around 22 hours) Control cells #1 #2 #3 #4 #5 #6 Cell number JAN ul. 2 2...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to grow in size (a) extracellular signals that stimulate cell division. d) produced by mitotic cells to keep nearby neighboring cells from dividing 7.) Which of the following cyclins is most active during mitosis? (a) cyclin A (b) cyclin B (c) cyclin C (d) cyclin D 8) Which molecule inactivate itotic cyclin-CDK complexes using phosphorylation? (a) Cdc25 (b) Cdc6 (c) Weel (d) Helicase 9.) What...
Question 31 2.3 pts What feature characterizes cancer cells? carefully regulated cell cycle uncontrollable cell division respond to density-dependent and anchorage dependent inhibition o divide by meiosis produce cells which are different from themselves
Question 26 (1 point) How is cytokinesis in plant cells different from cytokinesis in animal cells? Cytokinesis in plant cells requires formation of a cell plate; cytokinesis in animal cells requires formation of a ring of actin. Cytokinesis in plant cells occurs during G2; cytokinesis in animal cells occurs in the M phase of the cell cycle. Cytokinesis in plant cell results in one large cell with two nuclei; cytokinesis in animal cells results in two cells, each with one...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
Question 36 1 pts 36. You have a population of mammalian cells growing in media containing enough growth factors. Which of the following graphs corresponds to these cells when their DNA content is analyzed 24 hours after they are induced to express high levels of a mutant form of Rb protein that cannot be phosphorylated? (Note: this cell line has its cell cycle around 22 hours) Control cells #1 #2 #3 #4 #5 #6 Cell number JAN ul. 2 2...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
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