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Contrast replication of leading and lagging strands in both prokaryotes and eukaryotes.

Contrast replication of leading and lagging strands in both prokaryotes and eukaryotes.

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In prokaryotic cells, there is only one point of origin, replication occurs in two opposing directions at the same time, and takes place in the cell cytoplasm. Eukaryotic cells on the other hand, have multiple points of origin, and use unidirectional replication within the nucleus of the cell. Prokaryotic cells possess one or two types of polymerases, whereas eukaryotes have four or more.

Replication also happens at a much faster rate in prokaryotic cells, than in eukaryotes. Some bacteria take only 40 minutes, while animal cells such as humans may take up to 400 hours. In addition, eukaryotes also have a distinct process for replicating the telomeres at the ends of their chromosomes. With their circular chromosomes, prokaryotes have no ends to synthesize. Lastly, the short replication in prokaryotes occurs almost continuously, but eukaryotic cells only undergo DNA replication during the S-phase of the cell cycle.

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