Question
Determine the most likely mode of inheritance
give two reasons for your conclusion about the mode of inheritance
give the genotype of every person in the last generation . if the genotype could be either AA or Aa, indicate that with A-.
126 GENETICS LABORATORY MANUAL Pedigree Mode: x_linked recessive Reasoning: 오모어 SO O Pedigree Mode: Auto Somal Recessue Reaso
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Answer #1

Pedigree C - X-linked recessive.

The male has one X-chromosome and one y chromosome. So, if the disorder is X-linked then only a single copy of the mutated allele will show its phenotype in males.

In the given pedigree only males are affected. So it might be possible that trait is X-linked recessive.

The male receives his X-chromosome from his mother and Y from his father. If the mother is carriers for X-linked recessive diseases. In the given case mother of affected male is the carrier. So the trait is X-linked recessive.

Pedigree D.

The recessive disorder is only expressed when they are present in homozygous conditions.

Dominant trait never misses any generation whereas recessive trait can miss one generation and reappear in the next generation.

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