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QUESTION 2 The frequency of the individuals with phenylketonuria (PKU, a recessive genetic disease) is approximately...
Gaucher disease is an autosomal recessive disease that occurs at a frequency of 1 in 76.7,...
Gaucher disease is an autosomal recessive disease that occurs at a frequency of 1 in 76.7, or q2 = 0.013. Let’s assume Gaucher disease is in mutation selection balance. Assuming a mutation rate of µ = 10-5, calculate the selection coefficient (s) against the allele.
Cystic fibrosis (CF) is caused by recessive loss-of-function mutations for a cell surface protein expressed in...
Cystic fibrosis (CF) is caused by recessive loss-of-function mutations for a cell surface protein expressed in the mucus membranes of intestines and lungs. Until recently, few affected individuals survived to reproductive age. In Caucasian populations, CF affects 1 infant in 2,500 births. What is the frequency of CF homozygotes? Based on the genotype frequency, what is the frequency of the CF allele? Given a selection coefficient of 1, what would be the mutation rate needed to keep CF in the...
Q3 Question 3 1 Point In a Hardy-Weinberg situation, suppose that cystic fibrosis (a rare genetic...
Q3 Question 3 1 Point In a Hardy-Weinberg situation, suppose that cystic fibrosis (a rare genetic disorder caused by having two recessive alleles) occurs in approximately 1 out of 1600 births in Canada. What is the estimated proportion of the population that would be carriers for the disorder? Q4 Question 4 2 Points For some genetically linked disorders, the survival of the heterozygous individual may be less than that of a homozygous dominant individual (while homozygous recessive individuals still have...
2.3 Problem 3 The Hardy-Weinberg equation is useful for predicting the percent of a hu- man...
2.3 Problem 3 The Hardy-Weinberg equation is useful for predicting the percent of a hu- man population that may be heterozygous carriers of recessive alleles for certain genetic diseases. Phenylketonuria (PKU) is a human metabolic dis- order that results in mental retardation if it is untreated in infancy. In the United States, one out of approximately 10.000 babies is born with the disor- der. Approximately what percent of the population are heterozygous carriers of the recessive PKU allele? If you...
In a population of mice a particular locus has two alleles A1 (dominant) and A2 (recessive)....
In a population of mice a particular locus has two alleles A1 (dominant) and A2 (recessive). There are 126 A1A1, 167 A1A2 and 88 A2A2. Is this population in Hardy-Weinberg equilibrium (3 pts)? In a population of Gragons, there are 3151 A1A1, 1678 A1A2 and 2014 A2A2 individuals. If the environment changes so that the homozygous recessive genotype suffers a reduction of fitness where its fitness is now 0.73, but the other genotypes are unaffected, what will be the frequency...
0 b) 0.21 c) 0.42 d) 0.49 e) 0.91 Problem 3: in humans, Rh-positive individuals have...
0 b) 0.21 c) 0.42 d) 0.49 e) 0.91 Problem 3: in humans, Rh-positive individuals have the Rh antigen on their red blood cells, while Rh. negative individuals do not. If the Rh-positive phenotype is produced by a dominant gene (A), and the Rh negative phenotype is due to its recessive ailele (a). what is the frequency of the Rh-positive allele if 84% of a population is Rh-positive? a) 0.04 b) 0.16 c) 0.48 d) 0.60 e) 0.84 Problem 4:...
The Kermode Spirit bear is an alternate phenotype of the species Ursus americanus (black bear) in...
The Kermode Spirit bear is an alternate phenotype of the species Ursus americanus (black bear) in British Columbia that has striking white fur. It was determined in 2001 that a single nucleotide change from G to A results in the replacement of Tyrosine with Cysteine at codon 289 in the melanocortin 1 receptor gene (mc1r; Ritland et al. 2001 Current Biology). This allele (W2) is recessive to the wildtype allele (W1), and occurs as a novel mutation in 1 out...
Which of the following statements regarding the Hardy-Weinberg Equation is TRUE? Answers: It can only be u...
Which of the following statements regarding the Hardy-Weinberg Equation is TRUE? Answers: It can only be used when allele and genotype frequencies remain constant across generations in a population It can only be used when allele and genotype frequencies change across generations in a population It has no assumptions It mathematically shows how recessive alleles in a population decrease over time It reveals when allele frequencies change over time in a population Assuming Hardy-Weinberg Equilibrium, what percentage of individuals in...
explain 1 or 2 molecular details in how epigenetics may allow melanoma cells to outsmart BRAF inhibitors **This is for a genetics course Seope: This science commentary claims that epigeneties pl...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
need help with this .. From the pages 571-587 attached below. 1a) Suppose a population of...
need help with this ..
From the pages 571-587 attached below.
1a) Suppose a population of guppies was infected with a
parasite. In that population a mutation results in a parasite
resistant genotype that spreads through the population through
natural selection. A subsequent mutation in the parasite results in
a genotype that is unaffected by the newly evolved resistant guppy
genotype. What is the name of the hypothesis that explains this
host parasite “arms race”.?
1b) What is this name...
Q3 Question 3 1 Point In a Hardy-Weinberg situation, suppose that cystic fibrosis (a rare genetic disorder caused by having two recessive alleles) occurs in approximately 1 out of 1600 births in Canada. What is the estimated proportion of the population that would be carriers for the disorder? Q4 Question 4 2 Points For some genetically linked disorders, the survival of the heterozygous individual may be less than that of a homozygous dominant individual (while homozygous recessive individuals still have...
2.3 Problem 3 The Hardy-Weinberg equation is useful for predicting the percent of a hu- man population that may be heterozygous carriers of recessive alleles for certain genetic diseases. Phenylketonuria (PKU) is a human metabolic dis- order that results in mental retardation if it is untreated in infancy. In the United States, one out of approximately 10.000 babies is born with the disor- der. Approximately what percent of the population are heterozygous carriers of the recessive PKU allele? If you...
0 b) 0.21 c) 0.42 d) 0.49 e) 0.91 Problem 3: in humans, Rh-positive individuals have the Rh antigen on their red blood cells, while Rh. negative individuals do not. If the Rh-positive phenotype is produced by a dominant gene (A), and the Rh negative phenotype is due to its recessive ailele (a). what is the frequency of the Rh-positive allele if 84% of a population is Rh-positive? a) 0.04 b) 0.16 c) 0.48 d) 0.60 e) 0.84 Problem 4:...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
need help with this ..
From the pages 571-587 attached below.
1a) Suppose a population of guppies was infected with a
parasite. In that population a mutation results in a parasite
resistant genotype that spreads through the population through
natural selection. A subsequent mutation in the parasite results in
a genotype that is unaffected by the newly evolved resistant guppy
genotype. What is the name of the hypothesis that explains this
host parasite “arms race”.?
1b) What is this name...
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