4) For each of the following reactions, indicate whether the reaction would work well. poorly, or...
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
6. For the following reactions tell whether they will react under Ss1 condition (EtOH, heat), Ss2 condition (Nal/acetone) or neither. Also indicate the product formed if any. (10 points) Mechanism Product (Sl or S2) Br TsO HaC ii. Br Br HC iv. H3C CH3 H3C OCH3
Unit 3 Hinw '3 SNİSNDELE2 1. Give the major product(s) for the following reactions. Indicate the mec reaction occurs, write "no reaction. s) in operation. If no KOC(CH) (CH COH b. H3C NaNH2 NHy Nal H3C H2CH-CH3 CH,COCH CH OH CH3 2. Give the mechanism of each of the following reactions. NaCN CH CH CHCN NaBr a. CH,CH,CH Br acetone HSCH,CH (CH) CSCH,CH3 HBr Cl + NaCI + CH OH NaOCH CH3OH Br CH OH CH3
Q1. Identify the reaction mechanism most likely to take place (E1, SN1, E2, SN2 or a combination of these) in each of the following cases. Draw the major product(s), include stereochemistry when relevant. Br -OtBu Br NaCN, DMF → CI Носна 1. Nal/acetone 2. NaCN/DMF NaoMe H2SO4 OH Lyon CN (CH3)2CO CI NaOH →
raw the organic products produced in each of the following reactions. For partial credit, indicate whether the reaction is an E1, E2, S1. or S2 reaction on the line provided. Show stereochemistry when relevant. (19 pts) H₂ CH₂ нстве CH,OH HS acetone CH, Br e 99 cach. 9 CEC-H DMF e KUN DMSO Осн. CH, OH, 50°C
1. Complete the following reactions (indicate all products and the mechanisms of the reactions). CI H2O/EVOH/60°C EtOK/EVOH HOJEOHIBO°C NaOH Br NaSCH DMF DMF OH TSCI A DBU - Ру.
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
6) Predict the major product in each of the following reactions and indicate if it came from an Sn1, S2, E1, or E2 reaction. H3C Br NaOme CH3 H2O H Br MeOH 'BUOK H Br DMSO H3C Br NaOme CH3 H20 MeOH H OTS ЕКОН
Part II - Reactions (16 marks] Draw the expected major product(s) for each of the following reactions. Question Answer 8. 1. NaH OH ? 2. OTs 9. NBS ? major product 10. Nal Br ? Acetone Br 11. 1. NaNH2 H3C-CECH ? 2. OTS 12. OH Br NaOH ? cyclic compound 13. OH HBT ? 14. ? OH cat. H2SO4 H20 Room temp. 15. Br MeOH
answer all three questions and circle the answers Which of the following reactions will not produce the major product given? Br CH3OH (racemic) OSO?CF3 NaBr acetone но н NaBr acetone Br CH3 H CH3 CH3CH2ONa HRCH H3C CH2CH3 CH2CH3 H11.8 - Level 1 Homework . Unanswered For the given reaction, predict the major and minor products. NaCN DMF Premise Response Drag and drop to match = A Major B Minor Unanswered - Submit H11.9 - Level 1 Homework. Unanswered For...