Question

involves mul confirm your pre gen's potency mune system, toxins, adher- gree of tissue Case Study 5.2 Jamie is a 48-year-old black woman who c department complaining of a are common into the emergency painful s the distinctive , and redness over th drainage n her garden and said she had transmission past 5 he left hand. She spends a lot of time outdoors working i de direct con nasty" mosquito bite on the top of that hon f increa transmission pretty nasty" mosquito o her doctor n d an oral antibiotic and was told it wo probably a mild infection from the insect bite. Nou dictate that she presents because her hand is increasingly pain. when having ul tight. and the drainage has worsened She before the swelling started. After 3 days o reventing the ct. Universal care that rec- as potentially ling and redness she went t fluids. Masks noticed that she had a fever this morning of 102.9 ommended if Laboratory test results today show a WBC count ent and 18,500 After in anticipated. de exposure. hospitalization the wound culture is found to be positive for methicillin-resistant Staphylococcus and conva- tate d by the aureus (MRSA). From your reading and experience ing microor- regarding infectious processes, answer the follow ing questions: de septice- ction in 1. Outline the process that is most likely occurring in Jamie's body 2. What is the probable source of this infection? 3. What would you expect for local and systemic clinical manifestations? 4. What diagnostic tests were used or could be used How could you differentiate between viral or bac- terial pathogens? who is r to the middle . What additional treatment measures would you rience anticipate? How is MRSA treated differently than lowing nonresistant pathogens? 6. What would be the potential complications? curring

Answer 1

1. Jamie is infected with Methicillin resistant Staphylococcus aureus. Thus infection begins with redness or rash with pus filled pimples. It then progresses to an open, inflamed area in the skin which drains out pus or fluid. If the infection is severe it can spread to the blood causing fever with chills.
2. The probable cause of the infection maybe due to the mosquito bite.
3. The clinical manifestations are:
Local:
• Cellulitis
• Pus filled boils
• Abscesses
• Sty
• Carbuncles
• Impetigo
• Rashes
Systemic:
• Endocarditis
• Gangrene
• Necrotizing fasciitis
• Osteomyelitis
• Septic arthritis
4. The diagnostic tests used are WBC count and wound culture. The other diagnostic tests that could be done are culture of blood and urine, biopsy, blood sample for rapid screening test using MRSA DNA material.
5. The additional treatment measures are incision and drainage of the pus. The treatment with antibiotics are based on the culture report to see with what drugs the wound is resistant to and start antibiotics accordingly.
6. The potential complications are:
• Permanent organ damage or death
• Endocarditis
• Kidney infection
• Pneumonia
• Necrotizing fasciitis
• Osteomyelitis
• Sepsis