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What are the four mechanisms that mediates transcriptional activation in addition to RNA interference during during...

What are the four mechanisms that mediates transcriptional activation in addition to RNA interference during during the regulation of eukaryotic gene expression

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Let us list them and describe them:

- Methylation system. This requires cytosines to be methylated in order to block transcription of a certain gene

- Polymerase complex assembly. Proper assembly is a crucial procces for transcription to occur, the regulation of this process is a mechanism to regulate transcription per se

- Transcription factors mechanism. Transcription will only start if the proper factors and enhancers are brought in place, regulation of such factors and enhancers availability regulates the transcription of the site

- Chromatin state. Methylation or acetylation of histones regulates the tightness of such histones over DNA, acetylation promotes expression while methylation prevents it

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