What do we mean when we said that receptor-ligand interactions are reversible? Why is this important?
What do we mean when we said that receptor-ligand interactions are reversible? Why is this important?
Homework Answers
ANSWER:
By reversible receptor ligand interaction we mean that the binding or attachment of the ligand on the receptor can be reverted once the process of activation or inactivation to be caused by the receptor ligand interaction is completed and the binding between the receptor and ligand is non- covalent binding and thus the receptor can be reused to carry another set of reactions.
This non covalent interaction is of great significance as the same ligand is available to interact with multiple receptor subtypes. Thus a small concentration of ligand can work for longer time period and can be reused by the receptors to have an effect.
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What do we mean when we said that receptor-ligand interactions
are reversible? Why is this important?
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1. Suggest what sort of binding interactions could be involved
in holding acetylcholine to the active site.
2. The ester bond of acetylcholine is hydrolysed by
acetylcholinesterase. Suggest a mechanism by which the enzyme
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3. Suggest how binding interactions might make acetylcholine
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Acetylcholine is the substrate for the enzyme
acetylcholinesterase.
1. Suggest what sort of binding interactions could be involved
in holding acetylcholine to the active site.
2. The ester bond of acetylcholine is hydrolysed by
acetylcholinesterase. Suggest a mechanism by which the enzyme
catalyses this reaction.
3. Suggest how binding interactions might make acetylcholine
more susceptible to hydrolysis.
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receptor and mimics the action of the natural ligand acetylcholine.
Structure II,...
answer. 10.) What do we mean by AM-to-PM conversion? Why is it bad? What can be done about it? 11.) With respect to the superheterodyne receiver what do we mean by image interference? Enhance your explanation using a simple example.
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