Question

Give one example of a ligand-receptor pair for each of the six generic types of cell signaling. Do not include the details of the pathway, just give its name and how/why it is important to the cell.

Line up the six generic types, using the generix names, according to soeed of the signaling process and give an explanation of the order that you determined.

I'm guessing the six types are:

GCPR

Receptor Tyrosine Kinase

Receptor Guanylyl Cyclase

Adhesion receptor (integrin)

Gated ion channel

Nuclear receptor

Answer 1

The various types of receptor and ligand combination can be found below,

The GCPR: The g protein-coupled receptor. This is called a G protein-linked receptor. These proteins are acted by neuropeptide which is regulating cortisol production.

The tyrosine kinases are receptors for growth factors or hormones. Hence it regulates the growth and normal functioning of the body

Receptor Guanylyl Cyclase: They are single mass transmembrane protein. They are activated by ligand calcium, the low intracellular calcium level.

Adhesion Receptor: They are required for stabilized binding of leucocyte. Hence leukocyte molecule acts as the ligand. These leukocytes are responsible for immune response. They are responsible for the normal recirculation of lymphoid tissue.

Gated Ion channel is also called an ionotropic receptor. This receptor is opening to sodium, potassium, and other chemical ions to pass through and also the neurotransmitter to pass through. They maintain the toxicity of the cell.

Nucleus receptor is ligand regulated transcription factors: They have the ligand as hormones, estrogen and progesterone and various thyroid function and hence they regulated the growth and reproductive activity.