page d REACTIONS 3 Predict the maier productis) of the folowing reactions it you believe twe...
10). (18 pts) Predict the structures of the products from each of the following S2 reactions. If no reaction is expected, write "No Rxn" Hас. H,с-о° Br A). н,с- он сH H,с. KBr сH, В). acetone он NaN С). ethanol Br CH3 кCN D). H,с. Br DMSO сн, SH но E) CH3 ethanol "сH,
9. Predict the major products for the following reactions. Show the stereochemistry of the products) when applicable.. (a) HIB ROOR (1) Hg(OAc), HO (2) NaBH (1) BH, THE (2) 1,0, OH Br. H.O Pt (1) Oso (2) NaHSOHO (1) 03 (2) DMS (1) CHCO,H (2) H0+ Page 2 of 2
1) SHOW WORK STEP By STEP
below is Figure 7-3
Recognizing Epimers Using Figure 7-3, identify the epimers of (a) D-allose, (b) D-gulose, and (c) D-ribose at C-2, C-3, and C-4. Answer Epimers differ by the configuration about only one carbon. (a) D-altrose (C-2), D-glucose (C-3), D-gulose (C-4) (b) D-idose (C-2), D-galactose (C-3), D-allose (C-4) (c) D-arabinose (C-2), D-xylose (C-3) (a) D-Aldoses Three carbons Four carbons Five carbons но не HO -OH н-с-он CH, OH D-Glyceraldehyde но-с-н H-C-OH снион D-Threose...
3. In the deuterium -labeled compound below predict the product (s) of the elimination reactions of the following elimination reaction and tell whether the alkene formed contains deuterium (D) or not. (20 pts) Н.с, сн, OH H2SO&(aq) (i) heat НС NAOCH2CH3 (ii) CH3CH2OH н CH3 heat (iii) Write a detail mechanism for the formation of the product in question 3(i)
2. (12 pts) Reactions Give the reagents or products to the following systems. If a reaction does not give a product, write "NR" for No Reaction. Provide the product with the highest yield. Assume 1 to 1 stoichiometry unless otherwise stated. Provide stereochemistry if applicable. NC heat но но H ETOH 1. SOCI2 2. Heat, Hас -о н Но H но ETOH 1. TsCl NC H но но Н 2. CH,ок, CH,он
4. Provide reasonable products or reactants for the reactions below. (a) (reaction of aldehyde/ketone) H' Η CHO HO (b) (esterification) you 3) HCI 1) NaOH 2) HCI (d) (reaction of aldehyde/ketone) Tollen's reagent (e) (reaction of aldehyde/ketone) но он H* (1) (reduction reaction) NaBH ELOH
C) Give the major organic products for the following reactions and show the mechanism for 1-3. Be sure to consider the regioselectivity of each reaction! Cн. Brz CHs н" 2 сн,он CHs Cl2 3 н,о но- CH Hа Pd/C Cн
Question 3 Draw the mechanism for the following transformations: Нас снз CH3 H-SO Hс Он Question 4: 1) Hg(OAc) H,o 2) NaBH Нас- CHy Н,с сн, Question 5: Predict the product(s) of the following reaction: 1) BH, THF 2) H2O2, NaOH CH2 H,с Question 6: Predict the products of each of the following reactions: CH3 Hас- На Ni - CH3
1. Predict the major organic products of the following reactions. Draw all stereoisomers that are formed. НО, OH 1 eq ,H2SO4 (assume H2O workup of reaction to neutralize product) 1. LDA 2. (assume H,O workup of reaction to neutralize product) 3. Hg(OAC)2 4. NaBH, EtOH 1eq HBr EtOH ambiente 1. Brz. CCL 2. NaOET, ETOH OH
8. Predict the major organic products of each of the following reaction conditions (20 points) 1) LiAIH diethylether н 4 2) Н-о Н.о KOH CrO,, H,SO,, H,О он acetone (co-solvent) 1) CH3MgBr, diethylether 2) Н-о 9. Show how you could synthesize the targeted products from the starting epoxides. Show all reagents and reaction conditions in the boxes above the reaction arrows Но Hас ОСHЗ но O