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Upon performing a Kirby-Bauer disc diffusion test using Staphylococcus aureus, you observe no zone of inhibition...

Upon performing a Kirby-Bauer disc diffusion test using Staphylococcus aureus, you observe no zone of inhibition with penicillin and a 15mm zone of inhibition with vancomycin. Based on these observation, which of the following conclusions is valid?

Staphylococcus aureus is resistant to penicillin and sensitive to vancomycin.
Staphylococcus aureus is resistant to both vancomycin and penicillin.
Staphylococcus aureus is resistant to penicillin but may or may not be sensitive to vancomycin.
Penicillin is bactericidal toward Staphylococcus aureus, and vancomycin is bacteriostatic toward S. aureus.
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Answer #1

Hey, welcome to Chegg. I hope my answer will be of some help to you. Thank you!

Zone of inhibition is represented by a circular shaped area around a antibiotic in which bacteria colonies are not present due to inhibition of growth.

No zone of inhibition represent resistance to penicillin. Staphylococcus aureus can freely multiply in the area.

A 15 mm zone of inhibition represent high bacteriocidal effect of vancomycin on Staphylococcus aureus.

So, the correct option is a. Staphylococcus aureus is resistant to penicillin and sensitive to vancomycin.

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