Question

Classify each statement according to whether it applies to general transcription factors only, specific transcription factors only, both, or neither These transcription factors are found in both prokaryotes and eukaryotes. These transcription factors are proteins. These transcription factors form part of the transcription complex. One of these transcription factors binds directly to the TATA box in the core promoter. These transcription factors bind to the operator. These transcription factors bind to enhancer sequences that may be distant from the promoter. During formation of the transcription complex, these transcription factors are the first proteins to bind to the promoter. These transcription factors include TFIID and TFIIE. These transcription factors are necessary to recruit RNA polymerase Il to the promoter and initiate transcription at the basal level. These transcription factors act in a tissue- or time- dependent manner to stimulate levels of transcription that are higher than the basal level. General transcription factors only Specific transcription factors only Both Neither

Answer 1

• General transcription factor characteristic:
  1. They are the transcription factor that are found in both prokaryotes and eukaryotes.
  2. These transcription factor are formed of proteins.
• Specific transcription factor characteristic:

1. These transcription factor binds to operator region.
2. These transcription factor binds directly to the TATA box.
3. These transcription factor binds to the enhancer region that are found to be present far from the promoter.
4. These transcription factors form part of transcription complex.
5. During the formation of transcription complex these are the transcription factor that first binds to the promoter region.
6. The transcription factor acts in a time and tissue dependent manner.
7. Example of these transcription factor are: TFIID and TFIIE

• The transcription factor that acts as both general and specific transcription factor are: These transcription factor are involved in recruiting RNA polymerase II to the promoter and start transcription at the basal.