frank has klinefelter syndrome (47, XXY)...
Homework Answers
Answer
Frank recieved the mutant chromosome from his Father
Nondisjunction occured in his Father during the First meiotic division.
Since, the mutant gene is present on X-chromosome of Father of Frank
Frank has also got this disease, therefore, the second chromosome of XXY combination must have been inherited from father.
Nondisjunction has occured at Meiosis- 1 Stage,
At meiosis -1 chromosomes separate (Not chromatids), therefore, one cell has recieved both chromosomes (XY)
Each chromosomes is made up of 2 chromatids.
At Meiosis -II chromatids separate. therefore, the sperm from such a cell recieves one chromatids from X and another chromatids from Y and forms XY combination
when this sperm with XY fuses with egg having X, there resultant zygote has XXY genotype
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