The answer is A.
Explanation:
Butyric acid and propanol in their neutral form(without protons) are soluble in water. This will favor the formation of products(neutral ones) which result in the ionization and extraction of the two compounds at the same time. This will make difficult to etract both. So neutral forms which is soluble in water is responsible for the difficulty in acid base extraction of i & ii.
Their pKa value are to diiferent enough for separation. pKa(butyric acid) = 4.82 and pKa(propanol) = 16
So this is not tge reason.
Deprotonated form of ii is not thqt stable enough to make it recovery problems. So this too is not the reason.
Lab 7: Question 8 Homework – Unanswered Why would an acid-base extraction procedure be inefficient in...
Lab 7: Question 8 Homework – Unanswered Why would an acid-base extraction procedure be inefficient in separating 1-111? LOHCOOH M 1,0 r.com O A Compounds II and III are water soluble in their neutral forms The pka values of ll and Ill are not different enough to enable selective deprotonation based on base strength Ос The deprotonated form of Il that is isolated after extraction is too stable to be protonated to recover neutral Il
Lab 7: Question 6 Homework - Unanswered Why should Il be protonated, rather than deprotonated, in order to make it water soluble for extraction from an organic solvent? ♡ on olemas O A The anion derived from Il is too strong and reactive a base to remain stable under aqueous extraction conditions Protonation of amines to form ammonium salts affords a less reactive salt compared to the deprotonation product O C Both a and b are correct
Lab 7: Question 7 Homework – Unanswered Why would it be relatively challenging to separate I and Il via an acid-base extraction? O A Only one of these is soluble in organic solvents O B Both are relatively neutral O C Compound II is more polar
Lab 7: Question 4 Homework. Unanswered What is the purpose of adding aqueous base to extract the acidic components of the unknown mixture? O A Acids and bases afford salts that are water soluble in this experiment O B It moves the compounds of interest to the aqueous layer It enables selective extraction by reacting a weak base and a strong acid followed by reacting a strong base and weak acid, O D all of the above