Question

Protecting groups are used in synthesis when a starting material contains multiple reactive sites. This neutralizes one of the reactive sites and makes it inert to the reaction conditions. The protecting group can then be selectively removed to re-form the reactive site. Analyze the molecule below and answer the three questions. H3 C CH3 SCH BV сна CHI ntify the protecting group. Which reagent was used to install this protecting group? Which reagent is used to remove the protecting group? O THP ether TBDMS or TBS ether TIPS ether TMS ether dihydropyran triisopropylsilyl chloride tert-butyldimethylsilyl chloride trimethylsilyl chloride O O CH3MgBr H2, Pd/C BuNtF OKMnO4 O O

Answer 1

Anwurucu (0) proleching group in TBDMG on Teu ether o (11) fert-butyldimethylsilyl chloride yued su protecking groups (24) Billy, deprebec%. Explanation 2 CH3 CH₃ Bro- OH + si - CC CH₂ ? Cleak-butyldimethyl wily/ Chloride H CH₂ Br. ,CH - اع -8 ccorg

BMC o viган), есен, а above can be written av Bren оте мр - он Эrt от Дм3 в Вилэг arry de protection Note Topsnes - bead-bully) dimebby/ wsily? CH3 o C — oti — сен, cң
TBDMS protect alcohol .