Question

tivities Electron pairs :0: :0: 9 H:03 :0—H I- Erase H-CC-HH-CC-H I- H-OH Write the first step of this aldol reaction using c
Nat Et Ethanol pe 1 pt The double cyclization (above) proceeds by formation of an enolate followed by two successive intramol
CHE COCHE + NHẠCH + HCOẠC. CO CHE cat. H D CO CHE sine has been prepared by a sequence beginning with a Mannich reaction betw
0 0
Add a comment Improve this question Transcribed image text
Answer #1

OH :0. dillute NaOH Н - - IlclH - H- C-C IUI H H H Mechanism: H I-0 - СИ HK :01 Nucleophile {from NaOH} © H 2:0 CH H-C- C - H

Add a comment
Know the answer?
Add Answer to:
tivities Electron pairs :0: :0: 9 H:03 :0—H I- Erase H-CC-HH-CC-H I- H-OH Write the first...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • СО cat. H + NH2CH3 + H2CO2C CO2CH3 CO CHE Cocaine has been prepared by a...

    СО cat. H + NH2CH3 + H2CO2C CO2CH3 CO CHE Cocaine has been prepared by a sequence beginning with a Mannich reaction between dimethyl acetonedicarboxylate, methylamine, and butanedial. The mechanism involves the following steps: 1. Following initial protonation of the carbonyl oxygen, nucleophilic attack by the amine forms carbinolamine 1; 2. Proton transfer and elimination of water forms iminium ion 2; he enol form of the dicarboxylate ester attacks the iminium ion to form adduct 3; 4. Adduct 3 tautomerizes...

  • The double cyclization (above) proceeds by formation of an enolate followed by two successive intramolecular Michael...

    The double cyclization (above) proceeds by formation of an enolate followed by two successive intramolecular Michael reactions. Write a detailed mechanism for this reaction on paper, then draw structural formulas for the reactant enolate and adduct enolate of the first Michael reaction in the window below. You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. Do not include lone pairs in your answer. They will not be considered in the grading. Draw enolates...

  • please don't use any abbreviations! like I don't know how to draw anything like oet or...

    please don't use any abbreviations! like I don't know how to draw anything like oet or an R group like please just draw out the whole thing! NaOH ethanol HO This reaction involves an intramolecular Michael reaction followed by an intramolecular aldol reaction. The steps involved are as follows: 1. Deprotonation to form enolate ion 1; 2. Cyclization via an intramolecular Michael reaction to form intermediate 2; 3. Deprotonation to form enolate ion 3; 4. Intramolecular aldol cyclization to form...

  • Homework marked this wrong. Not sure what I did wrong Nat -OET ethanol This reaction involves...

    Homework marked this wrong. Not sure what I did wrong Nat -OET ethanol This reaction involves two successive Michael reactions, and has the following steps: 1. Deprotonation forms enolate ion 1; 2. The first Michael reaction forms enolate ion 2; 3. The second Michael reaction forms enolate ion 3; 4. Protonation leads to the final product. Write the mechanism out on a sheet of paper, and then draw the structure of enolate ion 2. • You do not have to...

  • please don't use any abbreviations! like I don't know how to draw anything like oet or...

    please don't use any abbreviations! like I don't know how to draw anything like oet or an R group like please just draw out the whole thing! CH3 CO2Et Hagemann's ester The compound known as Hagemann's ester is prepared by treatment of a mixture of formaldehyde and ethyl acetoacetate with base, followed by acid-catalyzed decarboxylation. The reaction involves the following steps: 1. Deprotonation of ethyl acetoacetate to form enolate ion 1; 2. Reaction of the enolate ion with formaldehyde to...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT