Question

THE laboratory The essential reactants guaifenesin synthesis are provided in Table 1. Table 1. Compound 2-methoxyphenol bp (°C) Reactants used amount used mmol 550 L calculate MW 124.14 d (g/mL) 1.13 NaOH (25% soln.) 40 do 1 mL obno ethanol 46.07 18 water 142.04 1.32 Sodium sulfate calculate 110.54 500 L (+)-3-chloro-1,2- propanediol 164

can you help me calculate the theoretical yield calculations for 2 methoxyphenol and 3-chloro-1,2-propanediol

Answer 1

1. Theoretical yield calculation for 2-mehoxyphenol:

2-mehoxyphenol is 550microlitre used that is 0.550gm used which gives 0.004430 mol =4.430mmol.

Molar mass of Guaifenesin is 198.21g/mol.and molar mass of 2-methoxyphenol is 124.14g/mol.

So, 198.21/124.14=1.5966*0.550=0.8781gm.

Hence , Theoretical yield for 2-mehoxyphenol is 0.8781gm.

2. Theoretical yield calculation for 3-chloro-1,2-propanediol:

3-chloro-1,2-propanediol is 500microlitre used that is 0.500gm used which gives 0.004523mol =4.4523mmol.

Molar mass of Guaifenesin is 198.21g/mol.and molar mass of 3-chloro-1,2propanediol is 110.24g/mol.

So, 198.21/110.24=1.7979*0.500=0.8989gm.

Hence , Theoretical yield for 3-chloro-1,2-propanediol is 0.8989gm.