Question

1. Which of the compounds below is expected to undergo Sg2 reaction to the highest degree? ~ a 2! The following substrate was subjected to a series of nucleophilic reactions. Which of the reagents below would be expected to progress climination reaction to the highest degree? elimination a) H.O b) Toso c) CH,COO d) HO el I Which of the following solvents should be correctly called aprotic solvent? M. a) aqua b) DMHA c) DMA d) MAC c) McОН The following substrate was subjected to a series of nucleophilic reactions. Which of the reagents below would be expected to progress substitution reaction to the highest degree? substitution .. a) I10 b) SIT c) t-Bu d) ITO S. Which of the following compounds is expected to undergo SNI reaction to the highest degree? yoyo 6. (2pts) More highly substituted alkenes are more stable. However, in an elimination of HX from alkyl halide using hindered base, less stable product predominates (Hoffman Rule). What is the expected major product in the following reaction? (CH2=CHO

Answer 1

Hence, among the given alkyl bromides, option c) Br has mole reactivity towards SN² reaction.

2. Strong nucleophiles favor substitution, and strong bases, especially strong hindered bases such as tert-butoxide favor elimination. Among the given options :- I, CH₂ Coo, Ho will favor substitution reactions. Between oth and Toso l a DESK Toso undergoes elimination more highly. Hence, Option o) is the answer.

3. Aprotic means non-protie solvents Protic means Htions. The solvents which cannot release Htions are called aprotic solvents. Among the given solvents, a) H H is a protic solvent. 6) HE OH is also a protic solvent. CH3 c) tz is also N-H CH₂ a protic solvent. d) He to is a aprotic solvent. e) the o t is a protic solvent.

Hence answer is to option f). Henco CH

5. The order of reactivity of alkyl-halides towards SN reactions is :- Benzyl > allys > >2 >1>methyl halidy a) y Br is alkyl halide. 6 or is in altgh halide. is allys alkyl halide. d) or is - allyl halide c) Dr is 2 alkyl Halide. Hence, answer is option or