Question

The __________________________________ pathway is critical for generating the precursor molecules erythrose-4-phosphate and ribose-5-phosphate along with NADPH for reducing power in anabolism.

Entner-Duodoroff (ED)

TCA

Reductive TCA

Pentose phospahte

Embden-Meyerhof (EMP)

Answer 1

Answer : Pentose phosphate pathway.

The pentose phosphate pathway is a metabolic pathway parallel to glycolysis. There are two distant pases in the pathway, the first is the oxidative phase, in which NADPH is generatedand the seconfd is the non oxidative synthesis of 5 - carbon sugars. The results of this pathway include:
1. Generation of reducing equivalents in the form of NADPH, used in reductive biosynthesis reactions within cells.
2. Production of erythrose 4-phosphate used in the synthesis of aromatic amino acids.
3.Production of ribose 5-phophate used in the synthesis of nucleotides and nucleic acids.

Other options are incorrect because:

Entner- Doudroff pathway describes a series of reactions that catabolize glucose to pyruvate usng a different set of enzymes from those used in either glycolysis or the pentose phosphate pathway.

Citric acid cycle also called as TCA cycle or kreb's cycle is series of chemical reactions used by aerobic organisms to release stored energy through the oxidation of acetyl- CoA derived from proteins, fats and carbohydrates into ATP and carbon dioxide.

Reverse TCA is a sequenece of chemical reactions that are used by some bacteria to produce carbondioxide and water.

Embden-Meyerhof pathway where the glucose is converted to pyruvate through a series of reactions. As a result small amount of ATP and NADH are also produced