For a deleterious mutation with s = −0.001, what is the probability of fixation in a population of size (a) Ne = 10, 000, (b) Ne = 1, 000, and (c) Ne = 100.
For a deleterious mutation with s = −0.001, what is the probability of fixation in a...
Imagine there is a co-dominant deleterious new mutation that arises in a population of size 1,000 diploid individuals. This mutation reduces fitness by 0.001 (s=0.001) in the heterozygous state. What is the probability that this mutation will become fixed in the population?
Genetics - Question 3 Defining heterozygosity, H, as the probability that two sequences randomly sampled from a population are different, for a diploid species with a population size of N = 1000 individuals and initial heterozygosity H0 = 0.5 ; a neutral mutation rate of u = 10-9, What is the rate of substitution with the above mutation rate? Explain. [5 marks] If, for beneficial mutation A1 the selection coefficient is s = 0.01, what is the probability of substitution...
Question 3 [20 marks] Defining heterozygosity, H, as the probability that two sequences randomly sampled from a population are different, for a diploid species with a population size of N = 1000 individuals and initial heterozygosity H0 = 0.5 What will the heterozygosity be after 100 generations? [3 marks] How many generations will it take to reduce the heterozygosity by half? [3 marks] With a neutral mutation rate of u = 10-9, what is the equilibrium value of heterozygosity? [3...
Assume h = 0.7 for a mildly deleterious mutation when homozygous (s = 0.05). In this case, the mutation rate to the deleterious form is 10−4. Assuming random mating, what is the equilibrium frequency for the mutant allele? A) 0.00286, B) 0.000314, C) 0.00116, D) 0.00222, E) 0.00346 Please explain, don't just give the answer.
Question 2 Part A [5 marks] If a new mutation for lactase persistence arises in a human population of size N = 10, what is the probability that the mutation will spread to fixation under each of the following scenarios? i a population with no culture of dairying, where the mutation is neutral ii a population with a culture of dairying, where the mutation has a selective advantage of s 0.1 Question 2 Part A [5 marks] If a new...
Given a population size of 100,000,000 (108) and a mutation rate of 0.001% calculate the number of expected mutants. Under what circumstances will these mutations increase in the population? Decrease? Remain constant?
What would happen if an allele under positive selection was linked to a deleterious mutation?(Do not copy others answers)!!
1. We're considering a fully recessive, deleterious (harmful) mutation (A2) at an allele frequency of q = 0.01 (one percent) in a large outbreeding population. Thus p(A1) = 0.99.1. What is the population frequency of A2A2 homozygotes? 2. What is the population frequency of A1A2 heterozygotes? 3. Of all the A2 alleles in the population, what proportion are in heterozygotes? 4. And what proportion are in homozygotes? 5. Now, your country starts a policy of sterilizing all the affected individuals...
What tends to happen to new mutations that are: Deleterious [Select Neutral [Select] Slightly beneficial [Select] Highly beneficial [Select] [Select It tends to go extinct quickly It tends to go to fixation quickly It tends to go to fixation slowly If it doesn't go extinct quickly, it tends to go to fixation Next 1 Previous
Question 18 1 pts The figure shows the effect of late-acting and early-acting deleterious mutations on survivorship curves. What do the differences in these curves mean for the evolution of senescence? A Late-acting mutation B Early-acting mutation C Comparison of survworship curves is decreased decreased from day 160 10 day 180 by Indviduels with 07 Time days Time days Click to view larger image. Selection acts more strongly on early-acting mutations, which are less likely to get eliminated from the...