Question

Classic rodent initiation promotion studies found that when animals were exposed only to a genotoxic initiator...

Classic rodent initiation promotion studies found that when animals were exposed only to a genotoxic initiator -

a.

They subsequently developed malignant tumors

b.

The animals developed skin tumors.

c.

They did not subsequently develop malignant tumors.

d.

Half of the animals developed malignant tumors.

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Answer #1

When animals are exposed to genotoxic initiator they can develop malignant tumors with due course of time as the genotoxic initiators causes changes in the genes which leads to cancer as the ability to repair the damage in DNA is reduced.

If skin is the only part exposed then only skin tumors are developed otherwise not.

Mostly all the animals develop malignant tumors, there is percentage in it.

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