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7. Predict the relative oxidation state (oxidized or reduced) of Q and...
7. Predict the relative oxidation state (oxidized or reduced) of Q and heme c, c1, Cua, and Cup for mitochondria treated with rotenone or antimycin A. Rotenone binds to Fe-S clusters in Complex I preventing electron transfer to Q. Antimycin A binds to one of the Q sites in Complex III preventing electron transfer from heme by to Q. Assume that electrons are continuously flowing from NADH & FADH2. Rotenone Antimycin A heme c1 Q (in the membrane heme c (Cytc) CUA CUB 8. When an antifungal drug is added to mitochondria, the QH2:Q ratio increases. Where in the electron transport chain does this drug inhibit electron transfer?