Question

1. Atrazine induces and promotes conversion of estrogen. 2. and are two receptors that acetylcholine bind to. Epibatidine and nicotine are agonists for 3. Regulatory mechanism between the hypothalamus and pituitary is that they regulate their own secretion/synthesis through 4. DDT can cause – _by binding to the 5. BPA acts as an obesogen by disrupting _and activating

Answer 1

Answer :

1) Atrazine induces FEMINISATION and promotes conversion of TESTOSTERONE to estrogen .

Explanation : Atrazine is a herbicide and is a known endocrine disruptor promoting complete feminisation .

2) NICOTINIC and MUSCARINIC are two receptors that acetylcholine bind to. Epibatidine and nicotine are agonists for NICOTINIC RECEPTORS.

Explanation :Acetylcholine is a neurotransmitter and it binds to two types of receptors muscarinic and nicotinic . Epibatidine is chlorinated alkaloid . Examples of nicotinic acetylcholine receptor binders or agonist are nicotine,epibatidine,acetylcholine,vernicline.

3) Regulatory mechanism between the hypothalamus and pituitary is that they regulate their own secretion /synthesis through FEEDBACK MECHANISM .

Explanation : Control of secretion of hypothalamic releasing factors and pituitary hormones is closely integrated by feedback loops and continuous interaction between hypothalamic pituitary adrenal axis.

4) DDT can cause ENDOCRINE DISRUPTION by binding to the ESTROGEN RECEPTORS.

Explanation : DDT is used as pesticide . It has been seen that it causes thinning of egg shells and feminisation in embryos in birds . In humans it is neurotoxic, endocrine disruptor and is found to interact with estrogen receptors . It is also supposed to promote breast cancer by interacting with estrogen receptors .

5) BPA acts as an obesogen by disrupting ENDOCRINE SYSTEM and activating ADIPOGENESIS.

Explanation :Bisphenol A acts as obesogen and endocrine disruptor . Obesogen disrupts normal lipid metabolism and promote abnormal lipid deposition causing obesity .