Question

3. Phlorotannins commonly found in brown algae are polymers of what oligomers? Name a synthetic method used to generate large numbers of compounds around a common chemical scaffold?

Answer 1

* Browar Algae (belongs to Phot Kingdom] Also called as kalps -> Technical terms of Brown Agae are pheophyla Pheophyceae Pigments present - chlorophyll a chlorophyllo, fucoxanthin pre-dominant pigment responsible for brown color A phlorotannins : They are a category of tannins with limited occurance of in nature, specifically present in algae and chemically are oligomers of Phlonglucinot A oligomers - are low molecular weight polymers comprising a small number of Repeat units. They are the intermediates of polymerization reaction. phloroglucinot Horoh OH ор 1,3,5-trihydroxybenzene Octaphlorelhed A [oligomer of phlorogleainet ] OH 매 40 DH 애 얘 odo HO Ho 애 HO OM ОР

Chemical Scaffold In ch The scaffold concept is applied to represent core structures of small molecules. -> They represent cove structures of bioactive compounds Ans :- is Solid phase chemistry / Solid-phase synthesis. - It was originally primarily used for synthesis of - peptides It has been adapted for the synthesis of small molecules as a tool to aid drug discovery. - The main driver for that change in emphasis was the need to produce large pools of compounds - This was achieved via The synthesis of combinations of compounds around a central Scaffold : a combinatorial Chemistry