Question

Part A Human ABO blood type is determined by three alleles, two of which (and P) produce gene products that modify the H antigen produced by protein activity of an independently assorting H gene. For this cross, what fraction will have type O blood? Express your answer as a fraction. Example: 1/8 For this cross, 4/8 will have type O blood. A rare abnormality known as the "Bombay phenotype" is the result of epistatic interaction between the gene for the ABO blood group and the H gene. Individuals with the Bombay phenotype appear to have blood type o based on the inability of both anti-A antibody and anti-B antibody to detect an antigen. The apparent blood type O in Bombay phenotype is due to the absence of H antigen as a result of homozygous recessive mutations of the H gene. Individuals with the Bombay phenotype have the hh genotype. Submit Previous Answers Request Answer x Incorrect; Try Again; 2 attempts remaining Use the information above to make predictions about the outcome of this cross: A, A HhxABHA Part B For this cross, what fraction will have type A blood? Express your answer as a fraction. Example: 1/8 For this cross, 3/16 will have type A blood. Submit Previous Answers Request Answer x Incorrect; Try Again; One attempt remaining Part For this cross, what fraction will have type AB blood? Express your answer as a fraction. Example: 1/8 For this cross, 6/16 will have type AB blood. Submit Previous Answers ✓ Correct Part D For this cross, what fraction will have type B blood? Express your answer as a fraction. Example: 1/8 For this cross, 3/16 will have type B blood. Submit Previous Answers Request Answer * Incorrect; Try Again; 2 attempts remaining

Answer 1

IaIa Hh × IaIb Hh

Gametes	IaH	Iah
IaH	IaIa HH (A)	IaIa Hh (A)
IbH	IaIb HH (AB)	IaIb Hh (AB)
Iah	IaIa Hh (A)	IaIa hh (O)
Ibh	IaIb Hh (AB)	IaIb hh (O)

A = 3/8

AB = 3/8

O = 2/8 = 1/4

B = 0

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