Question

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1. Phagocytosis of aged, damaged, or otherwise unwanted cells makes use of PRRs that recognize:

   1. Damage-associated molecular patterns

   2. Pathogen-associated molecular patterns

   3. Peptidoglycan

   4. Double-stranded RNA

   5. All of the above

2. Which of the following statements about phagocytosis is FALSE?

   2. Phagocytes move toward an area of infection by a process called chemotaxis

   3. The phagolysosome is a vacuole in which bacteria are exposed to degradative enzymes

   4. Phagocytes have receptors that recognize complement proteins bound to bacteria

   5. Phagocytes do NOT have receptors that recognize bacteria directly

3. Normal flora can have a protective role via:

   3. Competitively excluding pathogens

   4. Producing toxic compounds

   5. Priming the innate defenses

   6. All of the above

4. Innate immunity uses a variety of receptors that share the property of:

   4. Binding antigens presented by dendritic cells

   5. All belonging to a single family of genes

   6. All recognize molecular patterns unique to and common in microbes

   7. Association with MHC I on the surface of most cell types

5. Two soluble pattern-recognition proteins that both function as opsonins, which enhance phagocytosis, AND that also activate complement are _ and _.

   5. C1 and fibrinogen

   6. Factor D and factor P

   7. Factor P and C1

   8. C-reactive protein and MBL

Answer 1

1. Phagocytosis of aged, damaged, or otherwise unwanted cells makes use of PRRs that recognize:

Ans: Pathogen-associated molecular patterns

2. Which of the following statements about phagocytosis is FALSE?

Ans: Phagocytes do NOT have receptors that recognize bacteria directly

3. Normal flora can have a protective role via:

Ans: Priming the innate defenses

4. Innate immunity uses a variety of receptors that share the property of:

Ans: Binding antigens presented by dendritic cells

5. Two soluble pattern-recognition proteins that both function as opsonins, which enhance phagocytosis, AND that also activate complement are _ and _.

Ans: C-reactive protein and MBL