Homework Answers
I believe the correct answer to be:
OOin A) p53 normally functions as a tumor supressor to stop the cell cycle after DNA damage occurs.
As the p53 acts as tumor supressor gene and make the cell head towards apoptosis whenever the DNA damage is irrepairable and whenever this gene is inactivated due to mutation, it results in cancer as the cell is no longer able to head towards apoptosis.
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Why do loss of function mutations in p53 often lead to mutations in other genes? See...
Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What...
Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What happens when cells do NOT respond to the cell cycle control system and divide excessively? Tumor Proto-oncogeno (for protein that stimulates coll division) 6 Y DNA Benign Tumor= Mutation withln a control region of DNA Malignant Tumor Mutated promoter Metastasis Normal growth-stimulating protein in excess Oncogene Tumor-Suppressor Genes Proto-oncogene utled tara gese Samor-auppresr gane Many proto-oncogenes code for growth factors /Deletive nonimenig Normel grewt...
Classify each of the following into whether it represents a nonmutated proto-oncogene or a tumor suppressor...
Classify each of the following into whether it represents a nonmutated proto-oncogene or a tumor suppressor gene. Proto-Oncogenes Tumor Supressor Genes Inhibitors of p53 Apoptosis is restrained Apoptosis is promoted Eventually become inactive Sufficient cyclin Inhibitors of cyclin Eventually become oncogenes Promoters of p53 Cell cycle is restrained Cell cycle occurs normally
Normally tumor suppressor genes inhibit the cell cycle. How do mutations in these genes affect the...
Normally tumor suppressor genes inhibit the cell cycle. How do mutations in these genes affect the function of the encoded proteins and the cell cycle? Be specific.
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A ge...
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A gene that inhibits the transition from G1 to S phase c. d. A gene that promotes cell growth, combined with a hyperactive promoter How would methylation of the promoter of the gene in question 3c affect the cell? Be specific using what you know about the...
There are two main types of cells in the human brain, neurons (nerve cells) and glial...
There are two main types of cells in the human brain, neurons (nerve cells) and glial cells (supporting cells). Once neurons fully mature, these nerve cells no longer divide. Glial cells, however, continue to divide over a person’s entire lifetime. GDNF (glial cell line-derived neurotrophic factor) is a small protein that stimulates growth in glial cells. What kind of signal molecule is this protein? How does GDNF likely promote cell division? After the glial cell receives GDNF, what will happen...
please help me with this genetics question! thank you! TS =Tumor Suppressor genes O = Oncogenes...
please help me with this genetics question! thank you!
TS =Tumor Suppressor genes
O = Oncogenes
5A. (12pts) Cancer is a genetic disease. Some of the causative mutations are Tumor Suppressor genes, and others convert proto-oncogenes into Oncogenes. In the list of properties below, mark an X in the column for TS, O, or both. TS O both Causes of inherited elevated cancer risk. Leads to uncontrolled cell growth. Typically, spontaneous, gain-of-function mutations. Can cause increased DNA damage. Dominant in...
1.The KRAS gene encodes the KRAS protein which functions to promote cell growth and division. A...
1.The KRAS gene encodes the KRAS protein which functions to promote cell growth and division. A single base-pair deletion occurs in exon 4 of the KRAS gene that results in an early stop codon. This mutation results in an unregulated KRAS protein that always sends growth signals. What is a correct classification of the normal (wildtype) KRAS gene? A) A tumor suppressor gene B) An oncogene C) A tumor activating gene D) A DNA repair gene E) A proto-oncogene 2....
Question 35 (1.5 points) Which of the following does NOT lead to cancer formation? mutant proto-oncogenes...
Question 35 (1.5 points) Which of the following does NOT lead to cancer formation? mutant proto-oncogenes mutant tumor suppressor genes passenger mutations mutant Rb Question 36 (1.5 points) The Cdk/cyclin complex can trigger cell division by removing Rb from E2F fixing damaged DNA O
what are the correct answers? 14. [1 pt] What is the correct classification of the mutant...
what are the correct answers?
14. [1 pt] What is the correct classification of the mutant Ras gene? o The mutant Ras gene is a tumor suppressor o The mutant Ras gene is a proto-oncogene • The mutant Ras gene is an oncogene o The mutant Ras gene is a DNA-repair gene o The mutant Ras gene is a malignant gene 15.[1 pt] A cell is heterozygous for the Ras mutation described above, the other Ras allele is wild type....
help me with that please this question is cery important i have a final , 7. Loss-of-function mutations in p53 typify the ajority of human cancers Discovery of the roles for p53 in the DNA damage...
help me with that please this question is cery important i
have a final ,
7. Loss-of-function mutations in p53 typify the ajority of human cancers Discovery of the roles for p53 in the DNA damage checkpoint and in apoptosis helps to explain its potency as a tumor suppressor protein. Recent studies suggest that p53 may possess an additional anti-tumor function: preventing telomerase activity. In one such study by Ogawa and colleagues, a human pancreatic cell line called MIA PaCa-2,...
Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What happens when cells do NOT respond to the cell cycle control system and divide excessively? Tumor Proto-oncogeno (for protein that stimulates coll division) 6 Y DNA Benign Tumor= Mutation withln a control region of DNA Malignant Tumor Mutated promoter Metastasis Normal growth-stimulating protein in excess Oncogene Tumor-Suppressor Genes Proto-oncogene utled tara gese Samor-auppresr gane Many proto-oncogenes code for growth factors /Deletive nonimenig Normel grewt...
Classify each of the following into whether it represents a nonmutated proto-oncogene or a tumor suppressor gene. Proto-Oncogenes Tumor Supressor Genes Inhibitors of p53 Apoptosis is restrained Apoptosis is promoted Eventually become inactive Sufficient cyclin Inhibitors of cyclin Eventually become oncogenes Promoters of p53 Cell cycle is restrained Cell cycle occurs normally
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A gene that inhibits the transition from G1 to S phase c. d. A gene that promotes cell growth, combined with a hyperactive promoter How would methylation of the promoter of the gene in question 3c affect the cell? Be specific using what you know about the...
please help me with this genetics question! thank you!
TS =Tumor Suppressor genes
O = Oncogenes
5A. (12pts) Cancer is a genetic disease. Some of the causative mutations are Tumor Suppressor genes, and others convert proto-oncogenes into Oncogenes. In the list of properties below, mark an X in the column for TS, O, or both. TS O both Causes of inherited elevated cancer risk. Leads to uncontrolled cell growth. Typically, spontaneous, gain-of-function mutations. Can cause increased DNA damage. Dominant in...
Question 35 (1.5 points) Which of the following does NOT lead to cancer formation? mutant proto-oncogenes mutant tumor suppressor genes passenger mutations mutant Rb Question 36 (1.5 points) The Cdk/cyclin complex can trigger cell division by removing Rb from E2F fixing damaged DNA O
what are the correct answers?
14. [1 pt] What is the correct classification of the mutant Ras gene? o The mutant Ras gene is a tumor suppressor o The mutant Ras gene is a proto-oncogene • The mutant Ras gene is an oncogene o The mutant Ras gene is a DNA-repair gene o The mutant Ras gene is a malignant gene 15.[1 pt] A cell is heterozygous for the Ras mutation described above, the other Ras allele is wild type....
help me with that please this question is cery important i
have a final ,
7. Loss-of-function mutations in p53 typify the ajority of human cancers Discovery of the roles for p53 in the DNA damage checkpoint and in apoptosis helps to explain its potency as a tumor suppressor protein. Recent studies suggest that p53 may possess an additional anti-tumor function: preventing telomerase activity. In one such study by Ogawa and colleagues, a human pancreatic cell line called MIA PaCa-2,...
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