Homework Answers
a. Oxygen consumption will increase in the addition of DNP since it bypasses the ATP synthase and increases in metabolism
DNP is known as the protonophore. It allows (increase) the passage of proton transport across the mitochondrial membrane
b. DNP will make the ATP synthesis less efficient and energy produced from cellular respiration is lost as heat. Because of
DNP uncouples the oxidative phosphorylation (process phosphorylation of ADP to form ATP) the ratio of ATP to ADP will
decrease
c. Since energy production is more inefficient in DNP use, the body will increase fat metabolism to meet the energy
requirements of the body. Fat metabolism will eventually result in body weight loss.
Add Answer to:
Consider what will happen to a cell if dinitrophenol (DNP) is added to cause a partial...
2,4-dinitrophenol (DNP) and carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP) are well known uncouplers that can dissipate the proton gradient across...
2,4-dinitrophenol (DNP) and carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP) are well known uncouplers that can dissipate the proton gradient across the inner mitochondrial membrane created by the electron-transport system. Explain how this uncoupling works, in terms of the chemical properties of DNP and FCCP.
1. 2,4-Dinitrophenol (DNP) is a molecule that can shuttle protons across cellular membranes and was used...
1. 2,4-Dinitrophenol (DNP) is a molecule that can shuttle protons across cellular membranes and was used in diet pills in the 1930s (but was quickly discontinued for its lethality). Explain how this molecule might induce weight loss, and why its consumption is often fatal. 2. Biosynthesis and breakdown of glucose share many common enzymes and reactions, but this is not the case in the metabolism of fatty acids. Compare and contrast fatty acid biosynthesis vs. beta-oxidation (location, acyl group carriers,...
need question answered 53. Dinitrophenol (DNP) is a molecule that can transport protons across the inner...
need question answered
53. Dinitrophenol (DNP) is a molecule that can transport protons across the inner mitochondrial membrane, cyanide prevents the reduction of O, by the cytochrome Coxidase complex Which of the two will inhibit the oxidation of reduced co m es Explain 1.5 points c LOR o ndanom (c the Cyanide job being to prevent the reduction Oh my so it un tote connor of the relucrat b. Which of them is an uncoupling agent? Explain 1.5 points Clanice...
2. What would happen to each of the following if reduced the supply of glucose to...
2. What would happen to each of the following if reduced the supply of glucose to cells by 50%? You may assume that the cell will NOT switch to an alternative energy source. Briefly explain why for each. A. The level of glycolysis activity. B. The level of Krebs Cycle activity. C. The level of activity in the electron transport chain in the mitochondria. D. The size of the proton gradient across the inner mitochondrial membrane. E. The rate of...
Q2. The release of ATP by the beta subunit is most directly dependent on: Select ONE...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions to flow down the concentration gradient and across the inner mitochondrial membrane without going through the ATP Synthase. Why would this be a problem for Cell Respiration? You may want to refer to your diagram of the ETC to help you. Answer this in 3-5 well crafted sentences. 7) Describe what happens to the free energy of the carbon molecules through Cell Respiration. Your...
Please help me figure these out, and if you could explain why you got the answer...
Please help me figure these out, and if you could explain why you got the answer you did that would be great, because I have an exam tomorrow! Thanks in advance. 1. Anaplerotic reactions __________. A. produce oxaloacetate and malate to maintain constant levels of citric acid cycle intermediates B. produce biotin needed by pyruvate carboxylase C. recycle pantothenate used to make CoA D. produce pyruvate and citrate to maintain constant levels of citric acid cycle intermediates E. All of...
1. The Mystery of the Seven Deaths-- The results in Part III suggests which process of...
1. The Mystery of the Seven Deaths--
The results in Part III suggests which process of respiration
[glycolysis, pyruvate processing, citric acid cycle, or the
electron transport chain] was affected? Why is this the process you
suspect [based on the results]?
Does cyanide poisoning increase ATP production or decrease it?
Explain your answer.
2. The effect of gramicidin--
List the one(s) that would remain the same.
List the one(s) that would decrease (or go to zero).
List the one(s) that...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
need question answered
53. Dinitrophenol (DNP) is a molecule that can transport protons across the inner mitochondrial membrane, cyanide prevents the reduction of O, by the cytochrome Coxidase complex Which of the two will inhibit the oxidation of reduced co m es Explain 1.5 points c LOR o ndanom (c the Cyanide job being to prevent the reduction Oh my so it un tote connor of the relucrat b. Which of them is an uncoupling agent? Explain 1.5 points Clanice...
2. What would happen to each of the following if reduced the supply of glucose to cells by 50%? You may assume that the cell will NOT switch to an alternative energy source. Briefly explain why for each. A. The level of glycolysis activity. B. The level of Krebs Cycle activity. C. The level of activity in the electron transport chain in the mitochondria. D. The size of the proton gradient across the inner mitochondrial membrane. E. The rate of...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions to flow down the concentration gradient and across the inner mitochondrial membrane without going through the ATP Synthase. Why would this be a problem for Cell Respiration? You may want to refer to your diagram of the ETC to help you. Answer this in 3-5 well crafted sentences. 7) Describe what happens to the free energy of the carbon molecules through Cell Respiration. Your...
1. The Mystery of the Seven Deaths--
The results in Part III suggests which process of respiration
[glycolysis, pyruvate processing, citric acid cycle, or the
electron transport chain] was affected? Why is this the process you
suspect [based on the results]?
Does cyanide poisoning increase ATP production or decrease it?
Explain your answer.
2. The effect of gramicidin--
List the one(s) that would remain the same.
List the one(s) that would decrease (or go to zero).
List the one(s) that...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
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