Question

1. The drawings below show the Origin of Replication for double stranded DNA a) prior to the DNA replication bubble being opened, and, b) after the replication bubble has been formed, and replication has been going on for a while. The orientation of the DNA template is indicated. Origin of Replication ม ๆ Using lines with arrowheads, show the leading and lagging strands within the replication bubble. Indicate the 5' and 3' ends of your molecules. Show the leading strand as one continuous fragment and the lagging strand as a series of a few fragments. 2. Here's an interesting one. Here's a DNA fragment, but the orientation of the DNA is reversed. As above, show the leading and lagging strands and label as above. Origin of Replication in in
I am having trouble with the second question. Could you please explain what the answer is and why? Thank you!

Answer 1

DNA replication is bidirectional.

and DNA polymerase adds new nucleotides to the 3`-OH of the existing nucleic acid so the polymerization occurs in 5` to 3` direction so the template strand having 3`- 5` direction the replication is continuous.

since the DNA replication is bidirectional, replication occurs in both directions.

  

SI lagging stand. leading strand lagging strand leading Strand