Question

Instructions: Briefly describe means provide a 1-4 sentence explanation. Name means providing a name is sufficient. a. 1. Fill-in each blank (a-j) with the most appropriate cell type. (9 pts) Resident phagocyte in body tissues that secretes numerous cytokines, chemokines and lipid mediators Immune responses by this cell type are dependent on MHC I molecules Most potent antigen-presenting cell (APC) type Chemical signals from these cells direct the development of hematopoietic cells along different lineages Produces antibodies _ First cell type recruited out of blood into tissue sites of infection Requires APCs to respond to pathogens Provides a physical barrier preventing entry of microbes into the body Capable of self-renewing and giving rise to all blood cell types 2. Use the picture below to answer the following questions. The structure labeled A represents an arterial blood vessel and the structure labeled V represents a venous blood vessel. [A given line can be used for more than one letter or not at all. Use each letter only once](12 pts) a. Identify a B cell follicle; put the letter "A" next to the correct line b. Identify a T cell-enriched location; 1; put the letter "B" next to the correct line c. Identify location where antigen-presenting cells from sites of infection enter this tissue put the letter "C" next to the correct line d. Identify location where T cells become activated put the letter "D" next to the correct line e. Identify location of active B cell proliferation; put the letter "E" next to the correct line f. Identify location where lymph leaves this tissue; put the letter "F" next to the correct line

Answer 1

a Macrophage

b. Cytotoxic T cell

c. Macrophages

d. Interleukin

e.  B lymphocytes ( plasma cell)

f. White blood cell

g.Dendritic cells

h. Skin

i. hematopoietic cell