Interpret this data. Why do you think bone marrow cells would be affected more than other cell types?
Answer :)
In the graph, the X-axis is showing the concentration of the drug while the Y-axis is showing the fraction of enzyme bound to the drug that is an inhibitor of the HIV enzyme. Drug 1 is giving highest binding to the enzyme at the 2 and 3 nM concentrations. While other drugs have the maximum capacity to binding with enzymes is nearly 80%. Therefore, drug 1 is the most effective drug.
Interpret this data. Why do you think bone marrow cells would be affected more than other...
4. A) At high doses, AZT had serious side effects especially on bone marrow cells. Based on the structure of AZT and how you think the inhibitor works, what do you think is the cause? B) The data below helps us to understand both how AZT affects the enzyme reverse transcriptase and how it may affect other cells. Interpret this data in light of your answers to part a. Why do you think bone marrow cells would be affected more...
O Fraction of Enzyme bound to Inhibitor HIV enzyme named above New Drug 1 OHIV enzyme named above New Drug 2 . HIV enzyme named above AZT 0 0.5 3 3,5 1 1.5 2 2.5 Concentration of Compound (nM) a) Two new drugs were developed that interact with the enzyme. The following data was acquired on this drug. Please interpret this data and tell me what it likely means. b) No binding of drug 1 or 2 was observed without...