Question

PROBLEM: Suppose you are a researcher developing a treatment for a new viral outbreak. While screening many candidate compounds, you discover one that has beneficial effects in infected mice. Other researchers have shown that in order to replicate, the virus requires a viral protease called ViPri to cleave a viral protein called RIPz. Your experiments suggest that the compound (which you call Novira) inhibits this pathway. You hypothesize that Novira inhibits transcription and/or translation of ViPr1 and/or RIPz. 1. Describe the experiments that could determine whether Novira inhibits transcription of ViPr1 and/or RIPz. Explain the possible outcomes of your experiments and how you would draw conclusions from each outcome.

Answer 1

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