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Explain how secondary active transport of sodium is involved in re-uptake of water

Explain how secondary active transport of sodium is involved in re-uptake of water

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1. Some body cells like small intestinal cells uses sodium glucose cotransporter to transport water across epithelial membrane where osmotic gradient is not present there.

2. In small intestine there is coupling of solute transport with water transport and this is done by cotransporter protein like Na+/glucose cotransporter.

3. The small intestinal cell transport water by cotransporter mechanism because small intestinal cells do not have water channel proteins and water permeability is extremely low in this cells.

4. Water transport in small intestinal cells is secondary to active sodium transport. Ths sodium and water transport is mainly depending on presence of D-glucose.

5. When Na+ is enters cell with the glucose which is pumped out towards the blood using 3Na+/2K+pump and glucose is transported out by facilitated diffusion. This transport of Na+ increases local osmotic pressure in intercellular spaces that generates osmotic water flow across epithelium.

6. So that water is cotransported alongwith Na+ and glucose is transported through sodium glucose cotransporter in epithelial cells of small intestine.

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