Question

If a piece of DNA has the sequence: ATGCCG, which of the following would indicate a...

If a piece of DNA has the sequence: ATGCCG, which of the following would indicate a base substitution mutation?

ATGCCG

ATGGCG

TACGGC

ATGAACCG

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Answer #1

Answer: Option 2 (ATGGCG) is correct because in this only one nucleotide is changed during DNA replication.

Base Substitution is a gene-level mutation in which one nucleotide is substituted with another nucleotide during DNA Replication. In this, only a single nucleotide is affected in gene sequence so as a result only one codon is affected.

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