Question

42 to 48 please

42. Hydroxymethylcytosine is an unusual base found in the DNA of T-even phages to A) cause mutations; B) speed up DNA synthesis; C) avoid detection and degradation by host restriction endonucleases; D) facilitate packaging 43. The E test is A) a rapid serological test used to detect the presence of Eastern equine encephalitis virus in cerebrospinal fluid.; B) a quantitative antibiotic sensitivity test that utilizes plastic strips impregnated with an antibiotic of interest.; C) used to quantify levels of IgE antibody in serum samples. D) used to measure esculine levels in pasteurized milk. 44. A screening system called the Ames test is used to detect A) cellular respiration rate; B) chemicals with carcinogenic potential; C) transformation frequency, D) drug resistance; E) oxygen requirement 45. A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the: A) therapeutic index (TI); B) Kirby-Bauer, C) antibiogram; D) E-test; E) MIC 46. In an influenza virus, the drug oseltamivir (Tamiflu) inhibits the neuraminidase activity therefore blocking the A) adsorption; B) uncoating; C) RNA replication; D) release; E) maturation of the virus. 47. The shortest period of time needed to kill all organisms in a sample at a specified temperature is the A) thermal death time (TDT); B) thermal death point (TDP); C) decimal reduction time (D value); D) z value. 48. A disinfectant with a phenol coefficient value of 228 is_potent than one with a phenol coefficient value of 15. A) more; B) less; C) similarly

Answer 1

42.

Hydroxmethylcytosine is an unusual base found in the DNA of T-even phages to c) avoid detection and degradation by host restriction endonucleases.

Hydroxymethyl groups are glucosylated after DNA synthesis which prevents degradation of Hydroxymethylcytosine containing DNA by restriction enzymes.

43.

The E test is b) quantitative antibiotic sensitivity test that utilizes plastic strips impregnated with an antibiotic of interest.

It is used to determine antibiotic susceptibility of an organism. This test provides information about the concentration of antibiotic required to inhibit the tested bacteria.

44.

A screening system called Ames test is used to detect b) Chemicals with carcinogenic potential.

Ames test is used to detect that a particular chemical causes mutation or not to the DNA of test organisms . DNA Mutation leads to cancer so, it is also useful to test carcinogenic potential of a chemical.

45.

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the

a) Therapeutic index (TI)

46.

In an Influenza virus, the drug oseltamivir (Tamiflu)inhibits the neuraminidase activity therefore blocking the D. release of the virus.

Neuraminidase enzyme expressed on the surface of influenza virus. This enzyme helps in release of virus from infected cell. When this enzyme is inhibited, the release of the virus stopped.

47.The shortest period of time needed to kill all organism is a sample at a specified temperature is the a) Thermal death time.

48.

A disinfectant with a phenol coefficient value of 228 is a) more potent than one with a phenol coefficient value of 15.

Phenol coefficient is a measure of effectiveness of disinfectants. It is determined by comparing the power of killing the microorganisms.

The greater coefficient means more effectiveness.