1) What does the Dorsal protein do in Drosophila?
2) Why is the Dorsal protein critical to development? Describe in detail.
1) Dorsal protein is found in developing flies for the development of dorsoventral polarity. It is a transcription factor responsible for activating or repressing the genes present in the zygote of the fly responsible for differentiation along the dorsoventral axis in early stages of development.
1) What does the Dorsal protein do in Drosophila? 2) Why is the Dorsal protein critical...
2) Why is the Dorsal protein critical to development in drosophila? Describe in detail.
ASSIGNMENT 1: DROSOPHILA IMAGINAL DISC DEVELOPMENT 1) In Drosophila, the legs, wings and other adult structures develop from imaginal discs. Briefly describe what an imaginal disc is and how it forms an adult structure. 2) Describe the antero-posterior patterning of the dorsal wing imaginal disc, including the major genes involved and their role in this patterning. 3) Describe the antero-posterior, dorso-ventral and proximo-distal patterning of the ventral leg imaginal disc, including the major genes involved and their role in patterning.
1. Describe a typical protein-protein interface, and what is required to allow for protein interactions. 2. Are NAD- and ATP-binding domains generally conserved or unique? Why? 3. Why do proteins have cofactors (what role do they serve)? 4. Describe the two ways proteins can interact with DNA, and the differences between both. Which is similar to the RNA recognition motif? 5. How do proteins differentiate between ssRNA, dsRNA, DNA-RNA hybrids, and dsDNA?
This question is about mechanisms of gene regulation in eukaryotes. a) In Drosophila melanogaster, Sex-lethal (Sxl) controls somatic sexual development. i. Describe the regulatory mechanism that leads to the presence of Sxl protein only in female early embryos. [4 marks] ii. Explain how this difference is maintained later in the life cycle [6 marks] b) List two RNA modifications present in eukaryotes. Describe in detail the function of one of these RNA modifications in a living cell. [6 marks] c)...
This question is about mechanisms of gene regulation in eukaryotes. a) In Drosophila melanogaster, Sex-lethal (Sxl) controls somatic sexual development. i. Describe the regulatory mechanism that leads to the presence of Sxl protein only in female early embryos. [4 marks] ii. Explain how this difference is maintained later in the life cycle [6 marks] b) List two RNA modifications present in eukaryotes. Describe in detail the function of one of these RNA modifications in a living cell. [6 marks] c)...
what does Adding alcohol to egg protein do to the protein
chemically ?
Question 21 4 pts What does adding rubbing alcohol to egg protein do to the protein (chemically)? HTML Editor BIUA -A IE x D 1 12pt Y Paragraph 0 words
Critical Thinking Question 1. Why are people, as a rule, able to avoid infections? 2. Why is the previous use of antibiotics a risk factor for the development of antibiotic-resistant microorganisms? 3. In order for a disease to be transmitted to a person, that person must be susceptible. Which susceptibility factors does a person have control over and how can he or she control these factors?
Why is it so important to be knowledgeable about teratogens? What are the "critical factors" that can also affect development? How do they influence prenatal development? How do they compare to teratogens?
1) The Shh (sonic hedgehog) signaling molecule is important for patterning the dorsal-ventral axis of the spinal cord. Briefly describe where Shh is expressed and how its expression patterns the spinal cord. 2)What is the role of the proliferating chondrocytes and hypertophic chondrocytes in bone development and bone growth? a) Proliferating chondrocytes: b) Hypertrophic chondrocytes:
1) Why do genes on the same chromosome not segregate with “Mendelian Genetics”? Why/How do the frequencies of their co-segregation vary depending on their exact location? 2) Why does separating the left/right halves versus the dorsal/ventral halves of a two-cell stage amphibian embryo yield different results? 3) Why does the transplantation of an early blastopore lip induce head formation, while a late blastopore lip induces a tail?