Question

John has the sex-linked recessive Duchenne muscular dystrophy, but his brother Jim is normal. Mary's family has no history of DMD. What is the probability that Mary & Jim's children will have DMD? O 0% 100% for boys, 50% for girls 50% for boys, 100% for girls 50% for girls 50% for boys

Answer 1

Answer The ceremeet answer for this question is gotion © 0% Explanation: Here we gaw that, tehn . Chow's muscular dystrophing but this brother fim is normal. mary is the wife of gim who has no affect of muscular dystrophy. That's why there was no Stance of DMD to their children. Detailed expianation. - OMD is inherited in an x-linked reassure discredere. X-linked recessive genetic discredere are condition caused for an abnormal gene on the x-elremo'some that means of can caused toy mutation on the x-bromozome. his every boy inherits an x-chromosome from mother and chromosome from his father, which is what makes him male. Girds get twox-Chrono - somes, one from each parent that means one from mother and one from father. хх хү (he) M2 Maher f a father Mother is always be a carrier of a disease not father is a carrier in any cisease ... of a man with OND can not pass the flawed gene to his sons because he gives a sona Y-Chromosome not an X-chromosome But he will certainly pass to his daughters because each daugenters inherits her father's only X-Gromosome. They will be then carriers 's disease and each of their sons will have

509chance of Developing the disease and 80 on. Disease inherited in an X-linked recessive pattern mostly affect males because a second x-chronco come usually protects Femare from showing symptoms. When a girl inherits a flawed dystrophin gene from one parent, the usually gets a healthy dystrophin gene from her other pancent giving her enough of the protein to protect her from the disease. Males who inherits the mutation get the disease because they have no second dystrophin geine to make up for the faulty one. So, Here we gard that Mary's family has no history of Doud. That is the reason Mary is not a carenier of this disease. so sim and mary both are normal and heathy. So a none of their children wil be affected. so chance of DND of their re carrier of mary affected then there was will se a possibility' of getting infection to their our coreen. John children has the possibility of getting infection. Asgohn was affected one of his x-chromosome are mutate or affected to he can pass this mutate x- Chromosome to of Ceir gine not Boy. Then this gone will be carrier of John and this wife will be affected then it could be passs their all of their child. Child is 0%. wil hented on then there ketens will