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You work for EvilCorp developing new poisons. You create a toxin that binds to a protein...
9. In the electron transport chain picture above, how do electrons move from protein complex I to protein c...
9. In the electron transport chain picture above, how do electrons move from protein complex I to protein complex II? 1. I need you to remember that "Q" is ubiquinone which gets reduced at proteins l & I, and oxidized at protein III. "Reduced" means gains electrons, "oxidized" means loses electrons. 2. I need you to remember how "Q" moves from protein I to protein Do you remember? Don't overthink it, Preeda. As far as scientists know right now, the...
3b) Would you expect rotenone to be more, less or equally poisonous as carbon monoxide? Explain...
3b) Would you expect rotenone to be more, less or equally
poisonous as carbon monoxide? Explain you answer. (10pt)
3. In the lab, metabolic poisons can be used to study ATP synthesis and oxygen consumption. The action of several metabolic poisons is given in the table below: Poison Oligomycin Carbon monoxide 2,4-dinitrophenol (DNP) Rotenone Action Binds and blocks the proton channel in ATP synthase Inhibits cytochrome oxidase Binds protons and moves them down their electrochemical gradient Blocks electron transfer at...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
Question 4 You are now convinced that you know the cause of death for these victims...
Question 4 You are now convinced that you know the cause of death for these victims and quickly report it back to the police as this is a very dangerous situation. After realizing that the electron transport chain was no longer functioning, you started to suspect poisoning and ran a blood test for various poisons that you knew affected the electron transport chain. The test of all seven patients came back positive for cyanide. Cyanide irreversibly binds to cytochrome c...
Now that you've explained it in your own words, swer the following questions 8. What are...
Now that you've explained it in your own words, swer the following questions 8. What are the two electron carrier molecules that feed electrons into the clectron transport system? 9. Using Figure 9.14 in your text, explain the overall concept of how ATP synthase uses the flow of hydrogen ions to produce ATP. 10. What is the role of the electron transport chain in forming the H gradient across the inner mitochondrial membrane? 11. Oxygen stabilizes the electrons by combining...
1. The Mystery of the Seven Deaths-- The results in Part III suggests which process of...
1. The Mystery of the Seven Deaths--
The results in Part III suggests which process of respiration
[glycolysis, pyruvate processing, citric acid cycle, or the
electron transport chain] was affected? Why is this the process you
suspect [based on the results]?
Does cyanide poisoning increase ATP production or decrease it?
Explain your answer.
2. The effect of gramicidin--
List the one(s) that would remain the same.
List the one(s) that would decrease (or go to zero).
List the one(s) that...
Q13 Cyanide is a deadly poison that attaches to cytochrome c oxidase, the last protein in...
Q13 Cyanide is a deadly poison that attaches to cytochrome c oxidase, the last protein in the electron transport chain before the terminal electron acceptor. Based on your knowledge of the electron transport chain, which statement below best describes the action of cyanide on the body? A. Cyanide does not allow the Krebs cycle to be completed by blocking acetyl CoA from entering this cycle. This action shuts down the entire process of cellular metabolism. B. Cyanide does not allow...
Part II – Autopsy Report • Immediate cause of death was hypoxia (suffocation or lack of...
Part II – Autopsy Report • Immediate cause of death was hypoxia (suffocation or lack of oxygen). • Tissue sections from heart, lung, kidney, and liver all show massive cell death. • Staining with specific dyes showed major mitochondrial damage within the affected tissues. • Oxygen levels in the patients’ blood were approximately 110 mm Hg (normal range is 75 – 100 mm Hg). Questions 1. Recalling your knowledge of the function of organelles, what function of the cells was...
Question 2 (2 points) Histone methylation is an example of what kind of regulation? O post...
Question 2 (2 points) Histone methylation is an example of what kind of regulation? O post translational modification O controlling the timing of a protein O protein degredation O protein localization In Cell Physiology lab you decide to explore mitochondrial function in presence of chemical blockers of the electron transport chain. First you isolate mitochondria using the protocol that you learned in a previous lab. Then you perform a series of separate and independent experiments. In each experiment you use...
The common molecule produced from all foods at the second stage of catabolism is A) ADP. B acetyl...
just checking my answers, except for number 10.
The common molecule produced from all foods at the second stage of catabolism is A) ADP. B acetyl-CoA. C) glucose. D) citric acid. Which group of compounds includes only low-energy molecules? 1. 2. Hih A)ATP; acetyl-CoA; NADH; FADH2 C) ADP: CO2; NADH; FADH2 DONO BADP: acetyl-CoA; NAD+:FAD-mau ADP: CO2: NAD+, FAD After O2 has been reduced in the electron transport chain, the oxygen atoms are part of what molecules? A) ATP 3....
9. In the electron transport chain picture above, how do electrons move from protein complex I to protein complex II? 1. I need you to remember that "Q" is ubiquinone which gets reduced at proteins l & I, and oxidized at protein III. "Reduced" means gains electrons, "oxidized" means loses electrons. 2. I need you to remember how "Q" moves from protein I to protein Do you remember? Don't overthink it, Preeda. As far as scientists know right now, the...
3b) Would you expect rotenone to be more, less or equally
poisonous as carbon monoxide? Explain you answer. (10pt)
3. In the lab, metabolic poisons can be used to study ATP synthesis and oxygen consumption. The action of several metabolic poisons is given in the table below: Poison Oligomycin Carbon monoxide 2,4-dinitrophenol (DNP) Rotenone Action Binds and blocks the proton channel in ATP synthase Inhibits cytochrome oxidase Binds protons and moves them down their electrochemical gradient Blocks electron transfer at...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
Now that you've explained it in your own words, swer the following questions 8. What are the two electron carrier molecules that feed electrons into the clectron transport system? 9. Using Figure 9.14 in your text, explain the overall concept of how ATP synthase uses the flow of hydrogen ions to produce ATP. 10. What is the role of the electron transport chain in forming the H gradient across the inner mitochondrial membrane? 11. Oxygen stabilizes the electrons by combining...
1. The Mystery of the Seven Deaths--
The results in Part III suggests which process of respiration
[glycolysis, pyruvate processing, citric acid cycle, or the
electron transport chain] was affected? Why is this the process you
suspect [based on the results]?
Does cyanide poisoning increase ATP production or decrease it?
Explain your answer.
2. The effect of gramicidin--
List the one(s) that would remain the same.
List the one(s) that would decrease (or go to zero).
List the one(s) that...
Question 2 (2 points) Histone methylation is an example of what kind of regulation? O post translational modification O controlling the timing of a protein O protein degredation O protein localization In Cell Physiology lab you decide to explore mitochondrial function in presence of chemical blockers of the electron transport chain. First you isolate mitochondria using the protocol that you learned in a previous lab. Then you perform a series of separate and independent experiments. In each experiment you use...
just checking my answers, except for number 10.
The common molecule produced from all foods at the second stage of catabolism is A) ADP. B acetyl-CoA. C) glucose. D) citric acid. Which group of compounds includes only low-energy molecules? 1. 2. Hih A)ATP; acetyl-CoA; NADH; FADH2 C) ADP: CO2; NADH; FADH2 DONO BADP: acetyl-CoA; NAD+:FAD-mau ADP: CO2: NAD+, FAD After O2 has been reduced in the electron transport chain, the oxygen atoms are part of what molecules? A) ATP 3....
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