Describe the signaling pathway through which survival signals inhibit apoptosis (i.e., the PI3 pathway).
It works through receptor tyrosine kinase pathway
Describe the signaling pathway through which survival signals inhibit apoptosis (i.e., the PI3 pathway).
-Trace the general mechanism by which a signal transduction pathway occurs (i.e. from signaling molecule to response) Describe the two ways in which signaling proteins act as molecular switches -Which amino acid residues do kinases typically add phosphate groups? Distinguish between the two types of G proteins -What proteins regulate GTP-binding protein (G proteins) in terms of activation and inactivation? - Distinguish between the three main classes of cell surface receptors. -Trace the general mechanism by which a signal transduction...
Explain using simple details and correspoding "ON" "OFF" signals. Describe signaling through the G-protein linked receptor. Be sure to include the details of the receptor the associating G protein and its subunits, and the events in the sequence they occur. Be sure to include the reset for every step that is activated. Describe the signaling pathway that involves cAMP and G proteins. Include how each step is rest. Include dephosphorylation events. Assume involvement of PKA
I would prefer if you described the PERK signaling pathway out of the 3. Thanks! The figure might help. Describe in detail 1 (out of the 3) ER stress signaling pathways. Include all of the signaling components of the pathway [ligand, receptor, secondary signaling molecule(s), effector(s), cellular response, etc.) and their specific function. m BiP BIP BiP PERK IRE1 ATF6 ER 33333333 Cytosol Translocation to Golgl, cleavage by S1P and S2P Constant degradation elF2a Nrf2 ) Keap! XBP1s ATFO Dissociation...
For the following, choose which one of the following statements is FALSE: The Bcl2 family of proteins… (a) can stimulate apoptosis. (b) can inhibit apoptosis. (c) are extracellular signaling proteins. (d) are intracellular proteins in a pathway.
What is the difference between graded and discrete signaling? Describe three ways in which signals may be combined to convey different meanings.
Retinoblastoma(Rb) is inactivated when a mitogen signal is received. This mitogen works through a signaling pathway that includes RAS. Describe each step that occurs from binding of the mitogen to turning on transcription of cell proliferation gene. Explain how and why mutations in Rb can lead to tumors.
Please give short and concise explanations as to what the figure provided actually means , why they are important to the research they have conducted, and what the pathways corresponds to/represent. Will rate / need ASAP ***Please support all information provided. This figure belongs to an article based on cancer research , I have provided the intro. RESEARCH ARTICLE Resistant state Sensitive state JAK21 PI3K pathway STAT STAT STATMAPK pathway MAPK pathway AKT ERK STAT ST BAD Liberation of BCL-X...
41. Which is NOT a component of the extrinsic pathway of apoptosis? a. TNF b. Bax c. Initiator caspase d. Executioner procaspase e. All of the above
Which of the following are ways that extracellular survival factors apoptosis? Stimulate Bad phosphorylation Stimulate activation of BH3 Stimulate antMAP phosphorylation Stimulate transcription of Bcl2 family proteins
4) A signaling pathway proceeds through three protein kinases that are sequentially activated by phosphorylation. In one case, the kinases are held in a signaling complex by a scaffold protein. In the other, the kinases are freely diffusing. Discuss the properties of these two types of organization in terms of the signal amplification, speed, and potential cross talk between signaling pathways. (10 Points)