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Retinoblastoma(Rb) is inactivated when a mitogen signal is received. This mitogen works through a signaling pathway...

Retinoblastoma(Rb) is inactivated when a mitogen signal is received. This mitogen works through a signaling pathway that includes RAS. Describe each step that occurs from binding of the mitogen to turning on transcription of cell proliferation gene. Explain how and why mutations in Rb can lead to tumors.

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