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Question 24 Which of the following is NOT a clinical feature of Megaloblastic anemia Fatigue Weakness Shortness of breath All
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Megaloblastic anemia is a disorder in which the bone marrow develops extremely large immature red blood cells (megaloblasts) which are structurally irregular. Bone marrow, the spongy material inside our bone produces the blood cells, viz RBC, WBC, and platelets. Anemia is a disease characterized by low levels of red blood cells. Red blood cells are released into the bloodstream from the marrow, where they migrate through the body supplying oxygen to the tissue for its vital activity. A deficiency in healthy, fully mature red blood cells can lead to fatigue, skin paleness, lightheadedness, and additional results.

Megaloblastic anemia has many different causes-the two most common causes are the deficiencies of either cobalamin (vitamin B12) or folate (vitamin B9). Those vitamins play an important role in red blood cell growth.

According to your query, all the given options are symptoms or clinical features of Megaloblastic anemia. That is the symptoms include fatigue, weakness, shortness of breath, abnormalities of the gastrointestinal system include vomiting, nausea and lack of appetite. Some people affected may develop a reddened, sore tongue. Such abnormalities may contribute to unintentional weight loss. There may also be mild liver enlargement and a minor yellowing of the skin(yellow skin tint) or eyes (jaundice).

To summarise the given options are all the clinical features of Megaloblastic anemia.

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