Homework Answers
Thalassemia is the quantitative hemoglobinopathies. Thalassemia is mainly due to the reduced synthesis of the globular proteins due to mutations. It is genetically inherited disorder from parents to child.
Sickle cell anemia is the qualitative hemoglobinopathies. In this disease normal production of globular proteins, but single aminoacid substitutions in the globular protein chains. It is also inherited disorder.
Hemoglobin c caused due to the abnormal hemoglobin. In this redblood cells break down earlier than normal. Hemoglobin c is mainly due to gene mutations.
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Question 27 Which of the following represents quantitative hemoglobinopathies? Thalassemia Sickle cell anemia All of the...
Match the following conditions with their definitions below: aplastic anemia mononucleosis sickle cell anemia hemochromatosis thalassemia...
Match the following conditions with their definitions below: aplastic anemia mononucleosis sickle cell anemia hemochromatosis thalassemia hemolytic anemia polycythemia vera hemophilia purpura 1. General increase in red blood cells (erythremia). 2. Excess iron deposits throughout the body 3. Hereditary condition characterized by abnormal crescent shape of erythrocytes and by destruction of red blood cells 4. Inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background 5. Infectious disease marked by increased numbers of leukocytes and...
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in...
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in the oxygen-carrying hemoglobin molecule in erythrocytes. Sickle-cell conditions have an autosomal recessive pattern of inheritance from parents. The sickle cell defect is a mutation of a single nucleotide of the hemoglobin B gene, which results in glutamic acid being substituted by a different amino acid at position 6. Hemoglobin with this mutation is referred to as Hbs, as opposed to the normal hemoglobin HbA....
All of the following regarding sickle cell anemia phenotype is true, except: a. Sickle cell trait...
All of the following regarding sickle cell anemia phenotype is true, except: a. Sickle cell trait in HbB/HbS heterozygotes gives them resistance to malaria b. Properties of oxyhemoglobin are severely affected by HbS substitution c. Both alleles in hemoglobin beta-chain (HbB) gene are mutated in a full-blown condition d. Solubility of deoxyhemoglobin is decreased
Use the following information to answer the next two questions. Sickle cell anemia is a disease...
Use the following information to answer the next two questions. Sickle cell anemia is a disease that is caused by a mutation in the gene that produces haemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces haemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell...
Which of the following statements about sickle cell anemia is INCORRECT? Select one: a. Prenatal diagnosis...
Which of the following statements about sickle cell anemia is INCORRECT? Select one: a. Prenatal diagnosis of sickle cell anemia can be made by examination of DNA from fetal cells obtained by amniocentesis. b. Red cells have a shorter than normal survival in the circulation c. No treatment is available. d. Newborn infants homozygous for the sickle cell gene have few symptoms because their red cells also contain a large amount of fetal hemoglobin as well as sickle cell hemoglobin...
QUESTION 60 0.33334 points (E "Sickle cell anemia is produced by a genetic defect in the...
QUESTION 60 0.33334 points (E "Sickle cell anemia is produced by a genetic defect in the amino acid sequence of hemoglobin. Persons who are homozygous for this allele have abnormal red blood cells, which characterize the disease. The blood cells of heterozygous persons appear normal and they are considered carriers. A test reveals that a man is heterozygous for the sickle cell allele but his wife is homozygous normal. What is the probability of their children will be carriers of...
Even though sickle-cell anemia is usually fatal to homozygous individuals, the disease persists because: Gene therapy...
Even though sickle-cell anemia is usually fatal to homozygous individuals, the disease persists because: Gene therapy has alleviated the condition The disease is carried on the dominant allele Individuals with one allele for sickle-cell anemia are resistant to malaria None of the above
Q 11. Which of the following statements is TRUE about Sickle cell anemia? (A) It is...
Q 11. Which of the following statements is TRUE about Sickle cell anemia? (A) It is caused by a genetic mutation in the beta-hemoglobin gene. (B) It confers heterozygote advantage against malaria (C) It results in abnormal, sickle-shaped erythrocytes. (D) All of the above. Q 12. Which of the following explains why a deleterious allele may persist in a population? (A) Random genetic drift (B) Balancing selection (C) Negative selection (D) Random genetic drift or balancing selection Q 13. Which...
My Study on Sickle Cell Anemia Research In 500 words, answer the following questions 1.Select your...
My Study on Sickle Cell Anemia Research In 500 words, answer the following questions 1.Select your study sample 2. How have you selected your sample? 3. How will you select your sample population and give the rationale behind your decision Please type the solution on the keyboard so that I can copy and paste Q. No 1. Answer : Sickle cell disease : It is defined as it is a chronic heriditory form of Anemia, in which the red blood...
A woman has a father with sickle-cell anemia, which is an autosomal recessive trait. She does not have symptoms of sickle-cell anemia. What is her genotype? (0.5 marks) b) She is about to start a fami...
A woman has a father with sickle-cell anemia, which is an autosomal recessive trait. She does not have symptoms of sickle-cell anemia. What is her genotype? (0.5 marks) b) She is about to start a family, and she knows that her partner’s mother has sickle-cell anemia, but he does not have the disease himself. What is the probability of them having a child with sickle-cell anemia? Demonstrate this using a Punnett square. (2.5 marks) c) If they have three children,...
Match the following conditions with their definitions below: aplastic anemia mononucleosis sickle cell anemia hemochromatosis thalassemia hemolytic anemia polycythemia vera hemophilia purpura 1. General increase in red blood cells (erythremia). 2. Excess iron deposits throughout the body 3. Hereditary condition characterized by abnormal crescent shape of erythrocytes and by destruction of red blood cells 4. Inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background 5. Infectious disease marked by increased numbers of leukocytes and...
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in the oxygen-carrying hemoglobin molecule in erythrocytes. Sickle-cell conditions have an autosomal recessive pattern of inheritance from parents. The sickle cell defect is a mutation of a single nucleotide of the hemoglobin B gene, which results in glutamic acid being substituted by a different amino acid at position 6. Hemoglobin with this mutation is referred to as Hbs, as opposed to the normal hemoglobin HbA....
Which of the following statements about sickle cell anemia is INCORRECT? Select one: a. Prenatal diagnosis of sickle cell anemia can be made by examination of DNA from fetal cells obtained by amniocentesis. b. Red cells have a shorter than normal survival in the circulation c. No treatment is available. d. Newborn infants homozygous for the sickle cell gene have few symptoms because their red cells also contain a large amount of fetal hemoglobin as well as sickle cell hemoglobin...
QUESTION 60 0.33334 points (E "Sickle cell anemia is produced by a genetic defect in the amino acid sequence of hemoglobin. Persons who are homozygous for this allele have abnormal red blood cells, which characterize the disease. The blood cells of heterozygous persons appear normal and they are considered carriers. A test reveals that a man is heterozygous for the sickle cell allele but his wife is homozygous normal. What is the probability of their children will be carriers of...
Even though sickle-cell anemia is usually fatal to homozygous individuals, the disease persists because: Gene therapy has alleviated the condition The disease is carried on the dominant allele Individuals with one allele for sickle-cell anemia are resistant to malaria None of the above
Q 11. Which of the following statements is TRUE about Sickle cell anemia? (A) It is caused by a genetic mutation in the beta-hemoglobin gene. (B) It confers heterozygote advantage against malaria (C) It results in abnormal, sickle-shaped erythrocytes. (D) All of the above. Q 12. Which of the following explains why a deleterious allele may persist in a population? (A) Random genetic drift (B) Balancing selection (C) Negative selection (D) Random genetic drift or balancing selection Q 13. Which...
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