Homework Answers
Option C is correct because
sickle cell allele are on recessive side and persons having one sickle cell allele are resistant to malaria
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Even though sickle-cell anemia is usually fatal to homozygous individuals, the disease persists because: Gene therapy...
5. Sickle-cell disease is an interesting genetic disease. Normal homozygous individuals (SS) have normal blood cells...
5. Sickle-cell disease is an interesting genetic disease. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Thus, many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells that readily collapse when deoxygenated. Although malaria cannot grow in these red blood cells, individuals often die because of the genetic defect. However, individuals with the heterozygous condition (Ss) have some...
If individuals with the sickle-cell hemoglobin are selected against, how is it that the mutated hemoglobin...
If individuals with the sickle-cell hemoglobin are selected against, how is it that the mutated hemoglobin gene persists in the human population? Choose the best answer. Individuals with sickle-cell disease (recessive homozygous) are best able to fight off malaria, so the gene persists in malarious areas. The monkey bread tree is not sensitive to temperature. When a non-sickle cell individual (dominant homozygous) mates with an individual with sickle-cell disease (recessive homozygous) the produce heterozygotes and that is how the mutated...
Explain how the allele that causes the fatal condition of sickle-cell anemia has been preserved in...
Explain how the allele that causes the fatal condition of sickle-cell anemia has been preserved in certain populations that are exposed to malaria. Why is sickle-cell anemia relatively frequent today even among populations who live in geographic regions where malaria is under control?
Use the following information to answer the next two questions. Sickle cell anemia is a disease...
Use the following information to answer the next two questions. Sickle cell anemia is a disease that is caused by a mutation in the gene that produces haemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces haemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele,...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell anemia. From this data, a) Calculate the frequency of the dominant and recessive alleles. 1-04-06 b) Calculate the genotype frequencies for individuals not carrying a sickle cell allele, carriers and individuals who have the disease.
Sickle cell disease is an autosomal recessive disease. Homozygous dominant (SS) and heterozygous (Ss) individuals will...
Sickle cell disease is an autosomal recessive disease. Homozygous dominant (SS) and heterozygous (Ss) individuals will be non-diseased, but homozygous recessive (ss) individuals will have the disease. A study of sickle cell disease in New York found that in a one year period: 1/1146 of all infants in the state were born with sickle cell disease 1/230 non-hispanic black infants were born with sickle cell disease 1/41,647 non-hispanic white infants were born with sickle cell disease 1/2,320 hispanic infants were...
In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with...
In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with two alleles: HBBA (wild-type) and HBBS (sickle-cell mutation). In one population, the frequency of individuals who do not suffer from sickle-cell anemia (HBBAHBBA and HBBAHBBS) is 0.9964. Assuming the population is in Hardy-Weinberg equilibrium, what is the frequency of the HBBS allele?
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two...
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two copies of the recessive allele to display “sickle cell disease”). However, sickle cell trait (the heterozygous condition) has a unique phenotype. a. How would you classify/describe sickle cell trait at the organismal level (complete, incomplete, or co-dominance)? Explain your reasoning. b. How would you classify/describe sickle cell trait at the molecular level (complete, incomplete, or co-dominance)? Explain your reasoning. (HINT: think about the hemoglobin...
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in...
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in the oxygen-carrying hemoglobin molecule in erythrocytes. Sickle-cell conditions have an autosomal recessive pattern of inheritance from parents. The sickle cell defect is a mutation of a single nucleotide of the hemoglobin B gene, which results in glutamic acid being substituted by a different amino acid at position 6. Hemoglobin with this mutation is referred to as Hbs, as opposed to the normal hemoglobin HbA....
If individuals with the sickle-cell hemoglobin are selected against, how is it that the mutated hemoglobin gene persists in the human population? Choose the best answer. Individuals with sickle-cell disease (recessive homozygous) are best able to fight off malaria, so the gene persists in malarious areas. The monkey bread tree is not sensitive to temperature. When a non-sickle cell individual (dominant homozygous) mates with an individual with sickle-cell disease (recessive homozygous) the produce heterozygotes and that is how the mutated...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell anemia. From this data, a) Calculate the frequency of the dominant and recessive alleles. 1-04-06 b) Calculate the genotype frequencies for individuals not carrying a sickle cell allele, carriers and individuals who have the disease.
Sickle-cell Anemia Study Sickle-cell anemia or Sickle-cell disease, is a hereditary disorder. characterized by aryabnormality in the oxygen-carrying hemoglobin molecule in erythrocytes. Sickle-cell conditions have an autosomal recessive pattern of inheritance from parents. The sickle cell defect is a mutation of a single nucleotide of the hemoglobin B gene, which results in glutamic acid being substituted by a different amino acid at position 6. Hemoglobin with this mutation is referred to as Hbs, as opposed to the normal hemoglobin HbA....
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